› 7owx

X-ray diffraction
1.93Å resolution

Structure of coiled-coil tetramer from SARS-CoV-2 spike stalk region

Released:
DOI: 10.2210/pdb7owx/pdb
PDB entry 7owx coloured by chain, front view.
PDB entry 7owx coloured by chain, side view.
PDB entry 7owx coloured by chain, top view.
Source organism: Severe acute respiratory syndrome coronavirus 2
Primary publication:
Structural polymorphism of coiled-coils from the stalk domain of SARS-CoV-2 spike protein.
Živič Z, Strmšek Ž, Novinec M, Lah J, Hadži S
OpenAccess logo FASEB J 36 e22199 (2022)
PMID: 35157347

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-144978 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Spike protein S2' Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 27 amino acids
Theoretical weight: 3.22 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Not provided
UniProt:
  • Canonical: P0DTC2 (Residues: 1177-1203; Coverage: 2%)
Gene names: 2, S

Ligands and Environments

2 bound ligands:
Ligand EDO 3 x EDO
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P212121
Unit cell:
a: 45.14Å b: 45.54Å c: 47.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.178 0.172 0.233
Expression system: Not provided

Quick links

Citations

2 citation in other articles

A conserved oligomerization domain in the disordered linker of coronavirus nucleocapsid proteins.
Zhao et al. (2023)
1 more