› 7oyr

X-ray diffraction
1.15Å resolution

Function and Biology Details

Reactions catalysed: 
H(2)CO(3) = CO(2) + H(2)O
Urea = cyanamide + H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133685 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Carbonic anhydrase 2 Chain: A
Molecule details ›
Chain: A
Length: 260 amino acids
Theoretical weight: 29.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P00918 (Residues: 1-260; Coverage: 100%)
Gene name: CA2
Sequence domains: Eukaryotic-type carbonic anhydrase
Hit3-t4 (MH181) Chains: B, C
Molecule details ›
Chains: B, C
Length: 6 amino acids
Theoretical weight: 700 Da
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
2 modified residues:
Ligand 65T 2 x 65T
Ligand PR9 2 x PR9

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P21
Unit cell:
a: 42.272Å b: 41.218Å c: 72.483Å
α: 90° β: 104.51° γ: 90°
R-values:
R R work R free
0.124 0.123 0.151
Expression systems:
  • Escherichia coli
  • Not provided

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