› 7p13

Electron Microscopy
2.29Å resolution

2.29 A Mycobacterium tuberculosis EspB.

Released:
DOI: 10.2210/pdb7p13/pdb
PDB entry 7p13 coloured by chain, front view.
PDB entry 7p13 coloured by chain, side view.
PDB entry 7p13 coloured by chain, top view.
Source organism: Mycobacterium tuberculosis H37Rv
Primary publication:
Priming mycobacterial ESX-secreted protein B to form a channel-like structure.
Gijsbers A, Vinciauskaite V, Siroy A, Gao Y, Tria G, Mathew A, Sánchez-Puig N, López-Iglesias C, Peters PJ, Ravelli RBG
Curr Res Struct Biol 3 153-164 (2021)
PMID: 34337436
Related structures: EMD-13154

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo heptamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161686 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ESX-1 secretion-associated protein EspB Chains: A, B, C, D, E, F, G
Molecule details ›
Chains: A, B, C, D, E, F, G
Length: 289 amino acids
Theoretical weight: 31.56 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WJD9 (Residues: 2-287; Coverage: 62%)
Gene names: MTV027.16c, Rv3881c, espB, mtb48
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.29Å
Relevant EMDB volumes: EMD-13154
Expression system: Escherichia coli

Quick links

Citations

6 citation in other articles

Uptake-independent killing of macrophages by extracellular Mycobacterium tuberculosis aggregates.
Toniolo et al. (2023)
5 more

49 mentions without citation

Careful selection of reference genes is required for reliable performance of RT-qPCR in human normal and cancer cell lines.
Jacob et al. (2013)
48 more