7p33

X-ray diffraction
2.79Å resolution

Epstein-Barr virus encoded Bcl-2 homolog BHRF-1 in complex with Bid BH3 peptide

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-136630 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Apoptosis regulator BHRF1 Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 173 amino acids
Theoretical weight: 19.85 KDa
Source organism: Human herpesvirus 4 strain B95-8
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P03182 (Residues: 1-160; Coverage: 84%)
Gene name: BHRF1
Sequence domains: Apoptosis regulator proteins, Bcl-2 family
BH3-interacting domain death agonist p11 Chains: F, G, H, I, J
Molecule details ›
Chains: F, G, H, I, J
Length: 34 amino acids
Theoretical weight: 3.69 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P55957 (Residues: 76-109; Coverage: 17%)
Gene name: BID

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P6522
Unit cell:
a: 94.208Å b: 94.208Å c: 455.582Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.232 0.23 0.274
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided