› 7p4a

X-ray diffraction
2.9Å resolution

Non-canonical Staphylococcus aureus pathogenicity island repression.

Released:
DOI: 10.2210/pdb7p4a/pdb
PDB entry 7p4a coloured by chain, front view.
PDB entry 7p4a coloured by chain, side view.
PDB entry 7p4a coloured by chain, top view.
Source organism: Staphylococcus aureus
Primary publication:
Non-canonical Staphylococcus aureus pathogenicity island repression.
Miguel-Romero L, Alqasmi M, Bacarizo J, Tan JA, Cogdell RJ, Chen J, Byron O, Christie GE, Marina A, Penadés JR
OpenAccess logo Nucleic Acids Res (2022)
PMID: 36200825

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-105509 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
HTH cro/C1-type domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 247 amino acids
Theoretical weight: 29.75 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O54475 (Residues: 1-247; Coverage: 100%)
Sequence domains: Helix-turn-helix
Sri Chains: D, E
Molecule details ›
Chains: D, E
Length: 52 amino acids
Theoretical weight: 6.28 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A659I9D5 (Residues: 1-52; Coverage: 100%)
Gene names: DQV00_12285, G6W84_14285, G6Y24_00280, GQX52_13050

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 14 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P6122
Unit cell:
a: 100.211Å b: 100.211Å c: 298.688Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.301 0.298 0.343
Expression systems:
  • Escherichia coli BL21(DE3)
  • Escherichia coli

Quick links

Citations

2 citation in other articles

Induction mechanisms and strategies underlying interprophage competition during polylysogeny.
Silpe et al. (2023)
1 more

1 mention without citation

Non-canonical Staphylococcus aureus pathogenicity island repression.
Miguel-Romero et al. (2022)