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The structure of E. coli MutL bound to a 3' resected DNA end

Source organisms:
Biochemical function: ATP-dependent DNA damage sensor activity
Biological process: mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication
Cellular component: mismatch repair complex

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF08676
Domain description: MutL C terminal dimerisation domain
Occurring in:
  1. DNA mismatch repair protein MutL
The deposited structure of PDB entry 7p8v contains 2 copies of Pfam domain PF08676 (MutL C terminal dimerisation domain) in DNA mismatch repair protein MutL. Showing 1 copy in chain A (this domain is out of the observed residue ranges!).

PF01119
Domain description: DNA mismatch repair protein, C-terminal domain
Occurring in:
  1. DNA mismatch repair protein MutL
The deposited structure of PDB entry 7p8v contains 2 copies of Pfam domain PF01119 (DNA mismatch repair protein, C-terminal domain) in DNA mismatch repair protein MutL. Showing 1 copy in chain A.

PF13589
Domain description: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Occurring in:
  1. DNA mismatch repair protein MutL
The deposited structure of PDB entry 7p8v contains 2 copies of Pfam domain PF13589 (Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase) in DNA mismatch repair protein MutL. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR014790
Domain description: MutL, C-terminal, dimerisation
Occurring in:
  1. DNA mismatch repair protein MutL
IPR013507
Domain description: DNA mismatch repair protein, S5 domain 2-like
Occurring in:
  1. DNA mismatch repair protein MutL
IPR036890
Domain description: Histidine kinase/HSP90-like ATPase superfamily
Occurring in:
  1. DNA mismatch repair protein MutL
IPR042121
Domain description: MutL, C-terminal domain, regulatory subdomain
Occurring in:
  1. DNA mismatch repair protein MutL
IPR042120
Domain description: MutL, C-terminal domain, dimerisation subdomain
Occurring in:
  1. DNA mismatch repair protein MutL
IPR037198
Domain description: MutL, C-terminal domain superfamily
Occurring in:
  1. DNA mismatch repair protein MutL
IPR014721
Domain description: Small ribosomal subunit protein uS5 domain 2-type fold, subgroup
Occurring in:
  1. DNA mismatch repair protein MutL
IPR020568
Domain description: Ribosomal protein uS5 domain 2-type superfamily
Occurring in:
  1. DNA mismatch repair protein MutL
IPR014762
Domain description: DNA mismatch repair, conserved site
Occurring in:
  1. DNA mismatch repair protein MutL
IPR002099
Domain description: DNA mismatch repair protein MutL/Mlh/PMS
Occurring in:
  1. DNA mismatch repair protein MutL
IPR038973
Domain description: DNA mismatch repair protein MutL/Mlh/Pms-like
Occurring in:
  1. DNA mismatch repair protein MutL
IPR020667
Domain description: DNA mismatch repair protein, MutL
Occurring in:
  1. DNA mismatch repair protein MutL

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