Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Neurotransmitter-gated ion-channel
- Gamma-aminobutyric acid A receptor/Glycine receptor alpha
- Gamma-aminobutyric-acid A receptor, beta subunit
- Gamma-aminobutyric-acid A receptor, alpha subunit
- Neurotransmitter-gated ion-channel ligand-binding domain superfamily
- Neurotransmitter-gated ion-channel transmembrane domain
- Neurotransmitter-gated ion-channel transmembrane domain superfamily
- Neuronal acetylcholine receptor
12 more domains
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-210610 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (7 distinct):
Gamma-aminobutyric acid receptor subunit alpha-1
Molecule details ›
Chain: A
Length: 368 amino acids
Theoretical weight: 41.99 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 368 amino acids
Theoretical weight: 41.99 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
P14867 (Residues: 32-339, 418-456; Coverage: 81%)
Sequence domains:
Gamma-aminobutyric acid receptor subunit beta-3
Molecule details ›
Chains: B, C, E
Length: 451 amino acids
Theoretical weight: 51.62 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 451 amino acids
Theoretical weight: 51.62 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P28472 (Residues: 26-332, 447-473; Coverage: 75%)
Sequence domains:
Gamma-aminobutyric acid receptor subunit alpha-1
Molecule details ›
Chain: D
Length: 411 amino acids
Theoretical weight: 47.06 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 411 amino acids
Theoretical weight: 47.06 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P14867 (Residues: 32-339, 418-456; Coverage: 81%)
Sequence domains:
