Protein Data Bank in Europe

Chain: A
Length: 2571 amino acids
Theoretical weight: 291.32 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:

• Canonical: P42345 (Residues: 1-258, 259-2549; Coverage: 100%)

Gene names: FRAP, FRAP1, FRAP2, MTOR, RAFT1, RAPT1
Sequence domains:

• Serine/threonine-protein kinase mTOR domain
• FAT domain
• FKBP12-rapamycin binding domain
• Phosphatidylinositol 3- and 4-kinase
• FATC domain

Chain: C
Length: 326 amino acids
Theoretical weight: 35.91 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:

• Canonical: Q9BVC4 (Residues: 1-326; Coverage: 100%)

Gene names: GBL, LST8, MLST8
Sequence domains: WD domain, G-beta repeat

Chain: E
Length: 1708 amino acids
Theoretical weight: 192.47 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:

• Canonical: Q6R327 (Residues: 1-1708; Coverage: 100%)

Gene names: KIAA1999, RICTOR
Sequence domains:

• Rapamycin-insensitive companion of mTOR, N-term
• Rapamycin-insensitive companion of mTOR, middle domain
• Rapamycin-insensitive companion of mTOR RasGEF_N domain
• Rapamycin-insensitive companion of mTOR, domain 5
• Rapamycin-insensitive companion of mTOR, phosphorylation-site

Chain: G
Length: 522 amino acids
Theoretical weight: 59.21 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:

• Canonical: Q9BPZ7 (Residues: 1-522; Coverage: 100%)

Gene names: MAPKAP1, MIP1, SIN1
Sequence domains:

• Stress-activated map kinase interacting protein 1 (SIN1)
• SAPK-interacting protein 1 (Sin1), middle CRIM domain
• SAPK-interacting protein 1 (Sin1), Pleckstrin-homology

Chain: I
Length: 409 amino acids
Theoretical weight: 46.37 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:

• Canonical: Q8TB45 (Residues: 1-409; Coverage: 100%)

Gene names: DEPDC6, DEPTOR
Sequence domains: Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)