› 7pht

Solution NMR

Structure of Insulin receptor's transmembrane domain

Released:
DOI: 10.2210/pdb7pht/pdb
PDB entry 7pht coloured by chain, ensemble of 20 models, front view.
PDB entry 7pht coloured by chain, ensemble of 20 models, side view.
PDB entry 7pht coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Bershatsky YV, Nadezhdin KD, Bocharova OV, Bocharov EV

Function and Biology Details

Reaction catalysed: 
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138931 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Insulin receptor subunit beta Chain: A
Molecule details ›
Chain: A
Length: 30 amino acids
Theoretical weight: 3.46 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P06213 (Residues: 953-982; Coverage: 2%)
Gene name: INSR
Sequence domains: Insulin receptor trans-membrane segment

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 99%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

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