› 7pko

Electron Microscopy
3.9Å resolution

CryoEM structure of Rotavirus NSP2

Released:
DOI: 10.2210/pdb7pko/pdb
PDB entry 7pko coloured by chain, front view.
PDB entry 7pko coloured by chain, side view.
PDB entry 7pko coloured by chain, top view.
Source organism: Rotavirus A
Primary publication:
Structural basis of rotavirus RNA chaperone displacement and RNA annealing.
Bravo JPK, Bartnik K, Venditti L, Acker J, Gail EH, Colyer A, Davidovich C, Lamb DC, Tuma R, Calabrese AN, Borodavka A
OpenAccess logo Proc Natl Acad Sci U S A 118 (2021)
PMID: 34615715
Related structures: EMD-13474

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-106966 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Non-structural protein 2 Chains: A, B, C, D, E, F, G, U
Molecule details ›
Chains: A, B, C, D, E, F, G, U
Length: 313 amino acids
Theoretical weight: 36.23 KDa
Source organism: Rotavirus A
Expression system: Escherichia coli
UniProt:
  • Canonical: A2T3P0 (Residues: 1-313; Coverage: 99%)
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.9Å
Relevant EMDB volumes: EMD-13474
Expression system: Escherichia coli

Quick links

Citations

1 review citation

The Role of the Host Cytoskeleton in the Formation and Dynamics of Rotavirus Viroplasms.
Vetter et al. (2024)
12 other articles

1 mention without citation

Cryo-EM structure of rotavirus B NSP2 reveals its unique tertiary architecture.
Chamera et al. (2024)