EC 2.4.2.12: Nicotinamide phosphoribosyltransferase
Reaction catalysed:
Nicotinamide D-ribonucleotide + diphosphate = nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate
Systematic name:
Nicotinamide-D-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase
Alternative Name(s):
- NMN diphosphorylase
- NMN pyrophosphorylase
- NMN synthetase
- Nicotinamide mononucleotide pyrophosphorylase
- Nicotinamide mononucleotide synthetase
- Nicotinamide-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase
GO terms
Biochemical function:
Biological process:
- adipose tissue development
- positive regulation of nitric-oxide synthase biosynthetic process
- rhythmic process
- positive regulation of transcription by RNA polymerase II
- NAD biosynthesis via nicotinamide riboside salvage pathway
- circadian regulation of gene expression
- pyridine nucleotide biosynthetic process
- NAD biosynthetic process
- insulin receptor signaling pathway
- positive regulation of cell population proliferation
- circadian rhythm
- cell-cell signaling
- signal transduction
Protein families (Pfam)
InterPro annotations