› 7ppr

X-ray diffraction
2.57Å resolution

The structure of UDP-glucose pyrophosphorylase from Aspergillus fumigatus

Released:
DOI: 10.2210/pdb7ppr/pdb
PDB entry 7ppr coloured by chain, front view.
PDB entry 7ppr coloured by chain, side view.
PDB entry 7ppr coloured by chain, top view.
Source organism: Aspergillus fumigatus
Entry authors: Morton S, Raimi OG, Yan K, van Aalten DMF

Function and Biology Details

Reaction catalysed: 
UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-175799 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
UTP--glucose-1-phosphate uridylyltransferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 492 amino acids
Theoretical weight: 54.88 KDa
Source organism: Aspergillus fumigatus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q4WAM5 (Residues: 25-511; Coverage: 95%)
Gene name: AFUA_7G01830
Sequence domains: UTP--glucose-1-phosphate uridylyltransferase

Ligands and Environments

2 bound ligands:
Ligand SO4 15 x SO4
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: I222
Unit cell:
a: 134.16Å b: 152.61Å c: 160.01Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.23 0.227 0.277
Expression system: Escherichia coli BL21(DE3)

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