› 7pru

Electron Microscopy
3.2Å resolution

Structure of CtAtm1 in the inward-facing partially occluded with cargo bound

Released:
DOI: 10.2210/pdb7pru/pdb
PDB entry 7pru coloured by chain, front view.
PDB entry 7pru coloured by chain, side view.
PDB entry 7pru coloured by chain, top view.
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
Primary publication:
Structures of Atm1 provide insight into [2Fe-2S] cluster export from mitochondria.
Li P, Hendricks AL, Wang Y, Villones RLE, Lindkvist-Petersson K, Meloni G, Cowan JA, Wang K, Gourdon P
OpenAccess logo Nat Commun 13 4339 (2022)
PMID: 35896548
Related structures: EMD-13610

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-124059 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Iron-sulfur clusters transporter ATM1, mitochondrial Chains: A, B
Molecule details ›
Chains: A, B
Length: 700 amino acids
Theoretical weight: 77.2 KDa
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: G0SBE6 (Residues: 1-700; Coverage: 100%)
Gene name: CTHT_0050000
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand GSH 2 x GSH
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.2Å
Relevant EMDB volumes: EMD-13610
Expression system: Saccharomyces cerevisiae

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Citations

1 review citation

Ferroptosis in cancer: From molecular mechanisms to therapeutic strategies.
Zhou et al. (2024)
6 other articles