› 7pva

X-ray diffraction
1.91Å resolution

1.9 Angstrom crystal structure of dimeric PorX, co-crystallized in the presence of zinc

Released:
DOI: 10.2210/pdb7pva/pdb
PDB entry 7pva coloured by chain, front view.
PDB entry 7pva coloured by chain, side view.
PDB entry 7pva coloured by chain, top view.
Source organism: Porphyromonas gingivalis W83
Primary publication:
Response regulator PorX coordinates oligonucleotide signalling and gene expression to control the secretion of virulence factors.
Schmitz C, Madej M, Nowakowska Z, Cuppari A, Jacula A, Ksiazek M, Mikruta K, Wisniewski J, Pudelko-Malik N, Saran A, Zeytuni N, Mlynarz P, Lamont RJ, Usón I, Siksnys V, Potempa J, Solà M
Nucleic Acids Res (2022)
PMID: 36464236

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181760 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Response regulatory domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 523 amino acids
Theoretical weight: 62.14 KDa
Source organism: Porphyromonas gingivalis W83
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q7MVV4 (Residues: 1-518; Coverage: 100%)
Gene name: PG_0928
Sequence domains:

Ligands and Environments

6 bound ligands:
Ligand MG 11 x MG
Ligand BEF 8 x BEF
Ligand ZN 6 x ZN
Ligand GOL 12 x GOL
Ligand FMT 16 x FMT
Ligand CL 2 x CL
1 modified residue:
Ligand MSE 80 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P1
Unit cell:
a: 61.48Å b: 77.29Å c: 138.83Å
α: 82.42° β: 81.61° γ: 76.51°
R-values:
R R work R free
0.159 0.159 0.192
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 mentions without citation

Synthesis, photocatalytic and antidiabetic properties of ZnO/PVA nanoparticles.
El-Dafrawy et al. (2021)
1 more