› 7q0r

Electron Microscopy
2.67Å resolution

Structure of the Candida albicans 80S ribosome in complex with blasticidin s

Released:
DOI: 10.2210/pdb7q0r/pdb
PDB entry 7q0r coloured by chain, front view.
PDB entry 7q0r coloured by chain, side view.
PDB entry 7q0r coloured by chain, top view.
Source organism: Candida albicans SC5314
Primary publication:
E-site drug specificity of the human pathogen Candida albicans ribosome.
Zgadzay Y, Kolosova O, Stetsenko A, Wu C, Bruchlen D, Usachev K, Validov S, Jenner L, Rogachev A, Yusupova G, Sachs MS, Guskov A, Yusupov M
OpenAccess logo Sci Adv 8 eabn1062 (2022)
PMID: 35613268
Related structures: EMD-13750

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero 80-mer (preferred)
PDBe Complex ID:
PDB-CPX-215562 (preferred)
Entry contents:
75 distinct polypeptide molecules
5 distinct RNA molecules
Macromolecules (80 distinct):
Large ribosomal subunit protein uL2 Chain: j
Molecule details ›
Chain: j
Length: 254 amino acids
Theoretical weight: 27.37 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PF08 (Residues: 1-254; Coverage: 100%)
Gene names: CAALFM_C111060CA, RPL2, orf19.2309.2
Sequence domains:
Large ribosomal subunit protein uL3 Chain: k
Molecule details ›
Chain: k
Length: 389 amino acids
Theoretical weight: 44.04 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: Q59LS1 (Residues: 1-389; Coverage: 100%)
Gene names: CAALFM_C209430WA, RPL3, orf19.1601
Sequence domains: Ribosomal protein L3
Large ribosomal subunit protein uL4 Chain: l
Molecule details ›
Chain: l
Length: 363 amino acids
Theoretical weight: 39.28 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PFV1 (Residues: 1-363; Coverage: 100%)
Gene names: CAALFM_C114110CA, RPL4, RPL4B, orf19.7217
Sequence domains:
Large ribosomal subunit protein uL18 Chain: m
Molecule details ›
Chain: m
Length: 298 amino acids
Theoretical weight: 34.56 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: Q5AGZ7 (Residues: 1-298; Coverage: 100%)
Gene names: CAALFM_C701790CA, RPL5, orf19.6541
Sequence domains:
Large ribosomal subunit protein eL6 Chain: n
Molecule details ›
Chain: n
Length: 176 amino acids
Theoretical weight: 19.8 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PCX8 (Residues: 1-176; Coverage: 100%)
Gene names: CAALFM_C103110WA, RPL6, orf19.3003.1
Sequence domains: Ribosomal protein L6e
Large ribosomal subunit protein uL30 Chain: o
Molecule details ›
Chain: o
Length: 241 amino acids
Theoretical weight: 27.45 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PDL6 (Residues: 1-241; Coverage: 100%)
Gene names: CAALFM_C105720WA, RPL7A, orf19.2478.1
Sequence domains:
Large ribosomal subunit protein eL8B Chain: p
Molecule details ›
Chain: p
Length: 262 amino acids
Theoretical weight: 28.55 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: Q5ANA1 (Residues: 1-262; Coverage: 100%)
Gene names: CAALFM_C305240CA, RPL81, RPL8B, orf19.6002
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Large ribosomal subunit protein uL6 Chain: q
Molecule details ›
Chain: q
Length: 191 amino acids
Theoretical weight: 21.76 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: Q5AEN2 (Residues: 1-191; Coverage: 100%)
Gene names: CAALFM_C302470CA, RPL9, RPL9B, orf19.236
Sequence domains: Ribosomal protein L6
Large ribosomal subunit protein uL16 Chain: r
Molecule details ›
Chain: r
Length: 220 amino acids
Theoretical weight: 25.24 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: Q5AIB8 (Residues: 1-220; Coverage: 100%)
Gene names: CAALFM_C102460WA, RPL10, orf19.2935
Sequence domains: Ribosomal protein L16p/L10e
Large ribosomal subunit protein uL5 Chain: s
Molecule details ›
Chain: s
Length: 174 amino acids
Theoretical weight: 19.86 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PHW1 (Residues: 1-174; Coverage: 100%)
Gene names: CAALFM_C206810CA, RPL11, RPL11B, orf19.2232
Sequence domains:
Large ribosomal subunit protein eL13 Chain: t
Molecule details ›
Chain: t
Length: 202 amino acids
Theoretical weight: 23.11 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: O59931 (Residues: 1-202; Coverage: 100%)
Gene names: CAALFM_C103020CA, Ca49C10.02, CaO19.10511, CaO19.2994, RPL13
Sequence domains: Ribosomal protein L13e
Large ribosomal subunit protein eL14 Chain: u
Molecule details ›
Chain: u
Length: 131 amino acids
Theoretical weight: 14.75 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PFL9 (Residues: 1-131; Coverage: 100%)
Gene names: CAALFM_C113050WA, RPL14, RPL14B, orf19.4931.1
Sequence domains: Ribosomal protein L14
Large ribosomal subunit protein eL15 Chain: v
Molecule details ›
Chain: v
Length: 204 amino acids
Theoretical weight: 24.39 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: Q5A6R1 (Residues: 1-204; Coverage: 100%)
Gene names: CAALFM_CR04100CA, RPL15, RPL15A, RPL15B, orf19.493
Sequence domains: Ribosomal L15
Large ribosomal subunit protein uL13 Chain: w
Molecule details ›
Chain: w
Length: 200 amino acids
Theoretical weight: 22.69 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: Q5AB87 (Residues: 1-200; Coverage: 100%)
Gene names: CAALFM_C100180WA, RPL16, RPL16A, orf19.6085
Sequence domains: Ribosomal protein L13
Large ribosomal subunit protein uL22 Chain: x
Molecule details ›
Chain: x
Length: 185 amino acids
Theoretical weight: 21 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: Q59TE0 (Residues: 1-185; Coverage: 100%)
Gene names: CAALFM_C204600CA, RPL17, RPL17B, orf19.4490
Sequence domains: Ribosomal protein L22p/L17e
Large ribosomal subunit protein eL18 Chain: y
Molecule details ›
Chain: y
Length: 186 amino acids
Theoretical weight: 20.82 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PK43 (Residues: 1-186; Coverage: 100%)
Gene names: CAALFM_C305100CA, RPL18, RPL18B, orf19.5982
Sequence domains: Ribosomal protein 60S L18 and 50S L18e
Large ribosomal subunit protein eL19 Chain: z
Molecule details ›
Chain: z
Length: 190 amino acids
Theoretical weight: 21.94 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PK40 (Residues: 1-190; Coverage: 100%)
Gene names: CAALFM_C304500CA, RPL19A, RPL19B, orf19.5904
Sequence domains: Ribosomal protein L19e
Large ribosomal subunit protein eL20 Chain: 0
Molecule details ›
Chain: 0
Length: 172 amino acids
Theoretical weight: 20.38 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PLC9 (Residues: 1-172; Coverage: 100%)
Gene names: CAALFM_C401520CA, RPL20, RPL20B, orf19.4632
Sequence domains: Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
Large ribosomal subunit protein eL21 Chain: 2
Molecule details ›
Chain: 2
Length: 160 amino acids
Theoretical weight: 18.05 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PGY0 (Residues: 1-160; Coverage: 100%)
Gene names: CAALFM_C203810CA, RPL21A, orf19.840
Sequence domains: Ribosomal protein L21e
Large ribosomal subunit protein eL22 Chain: 5
Molecule details ›
Chain: 5
Length: 124 amino acids
Theoretical weight: 14.11 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PM41 (Residues: 1-124; Coverage: 100%)
Gene names: CAALFM_C404390WA, RPL22B, orf19.1409.1
Sequence domains: Ribosomal L22e protein family
Large ribosomal subunit protein uL14 Chain: 6
Molecule details ›
Chain: 6
Length: 137 amino acids
Theoretical weight: 14.51 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PPT5 (Residues: 1-137; Coverage: 100%)
Gene names: CAALFM_C602070CA, RPL23A, RPL23B, orf19.3504
Sequence domains: Ribosomal protein L14p/L23e
Large ribosomal subunit protein eL24 Chain: 7
Molecule details ›
Chain: 7
Length: 155 amino acids
Theoretical weight: 17.43 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: Q5A6A1 (Residues: 1-155; Coverage: 100%)
Gene names: CAALFM_C404890CA, RPL24, RPL24A, orf19.3789
Sequence domains: Ribosomal protein L24e
Large ribosomal subunit protein uL23 Chain: 8
Molecule details ›
Chain: 8
Length: 142 amino acids
Theoretical weight: 15.87 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PPS1 (Residues: 1-142; Coverage: 100%)
Gene names: CAALFM_C601970CA, RPL25, orf19.687.1
Sequence domains:
Large ribosomal subunit protein uL24 Chain: 9
Molecule details ›
Chain: 9
Length: 127 amino acids
Theoretical weight: 14.22 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PCQ5 (Residues: 1-127; Coverage: 100%)
Gene names: CAALFM_C102330CA, RPL26B, orf19.3690.2
Sequence domains: Ribosomal proteins L26 eukaryotic, L24P archaeal
Large ribosomal subunit protein eL27 Chain: AA
Molecule details ›
Chain: AA
Length: 136 amino acids
Theoretical weight: 15.55 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PFG4 (Residues: 1-136; Coverage: 100%)
Gene names: CAALFM_C112390CA, RPL27A
Sequence domains: Ribosomal L27e protein family
Large ribosomal subunit protein uL15 Chain: AB
Molecule details ›
Chain: AB
Length: 149 amino acids
Theoretical weight: 16.7 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PSC5 (Residues: 1-149; Coverage: 100%)
Gene names: CAALFM_CR03030CA, RPL28, orf19.2864.1
Sequence domains: Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
Large ribosomal subunit protein eL29 Chain: AC
Molecule details ›
Chain: AC
Length: 63 amino acids
Theoretical weight: 7.14 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PF57 (Residues: 1-63; Coverage: 100%)
Gene names: CAALFM_C111040WA, RPL29, orf19.2310.1
Sequence domains: Ribosomal L29e protein family
Large ribosomal subunit protein eL30 Chain: AD
Molecule details ›
Chain: AD
Length: 106 amino acids
Theoretical weight: 11.52 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PM75 (Residues: 1-106; Coverage: 100%)
Gene names: CAALFM_C404900WA, RPL30, orf19.3788.1
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Large ribosomal subunit protein eL31 Chain: AE
Molecule details ›
Chain: AE
Length: 112 amino acids
Theoretical weight: 12.99 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PHF5 (Residues: 1-112; Coverage: 100%)
Gene names: CAALFM_C205410WA, RPL31B, orf19.3572.3
Sequence domains: Ribosomal protein L31e
Large ribosomal subunit protein eL32 Chain: AF
Molecule details ›
Chain: AF
Length: 131 amino acids
Theoretical weight: 14.99 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PPN6 (Residues: 1-131; Coverage: 100%)
Gene names: CAALFM_C601700WA, RPL32
Sequence domains: Ribosomal protein L32
Large ribosomal subunit protein eL33 Chain: AG
Molecule details ›
Chain: AG
Length: 107 amino acids
Theoretical weight: 12.14 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PHH4 (Residues: 1-107; Coverage: 100%)
Gene names: CAALFM_C205710CA, RPL33, RPL33A, orf19.6882.1
Sequence domains: Ribosomal protein L35Ae
Large ribosomal subunit protein eL34 Chain: AH
Molecule details ›
Chain: AH
Length: 122 amino acids
Theoretical weight: 13.77 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PDZ1 (Residues: 1-122; Coverage: 100%)
Gene names: CAALFM_C106890CA, RPL34B, orf19.6220.4
Sequence domains: Ribosomal protein L34e
Large ribosomal subunit protein uL29 Chain: AI
Molecule details ›
Chain: AI
Length: 120 amino acids
Theoretical weight: 14.12 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PK30 (Residues: 1-120; Coverage: 100%)
Gene names: CAALFM_C304960WA, RPL35, orf19.5964.2
Sequence domains: Ribosomal L29 protein
Large ribosomal subunit protein eL36 Chain: AJ
Molecule details ›
Chain: AJ
Length: 99 amino acids
Theoretical weight: 11.1 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PH21 (Residues: 1-99; Coverage: 100%)
Gene names: CAALFM_C203960WA, RPL36
Sequence domains: Ribosomal protein L36e
Large ribosomal subunit protein eL37 Chain: AK
Molecule details ›
Chain: AK
Length: 90 amino acids
Theoretical weight: 10.1 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PF45 (Residues: 1-90; Coverage: 100%)
Gene names: CAALFM_C111360WA, RPL37B, orf19.667.1
Sequence domains: Ribosomal protein L37e
Large ribosomal subunit protein eL38 Chain: AL
Molecule details ›
Chain: AL
Length: 78 amino acids
Theoretical weight: 8.91 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PG16 (Residues: 1-78; Coverage: 100%)
Gene names: CAALFM_C200210WA, RPL38, orf19.2111.2
Sequence domains: Ribosomal L38e protein family
Large ribosomal subunit protein eL39 Chain: AM
Molecule details ›
Chain: AM
Length: 51 amino acids
Theoretical weight: 6.35 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PDT4 (Residues: 1-51; Coverage: 100%)
Gene names: CAALFM_C106470WA, RPL39
Sequence domains: Ribosomal L39 protein
Large ribosomal subunit protein eL40 Chain: AN
Molecule details ›
Chain: AN
Length: 52 amino acids
Theoretical weight: 6.08 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PL68 (Residues: 1-52; Coverage: 100%)
Gene names: CAALFM_C401050CA, RPL40B, orf19.4684.2
Sequence domains: Ribosomal L40e family
60S ribosomal protein L41 Chain: AO
Molecule details ›
Chain: AO
Length: 25 amino acids
Theoretical weight: 3.4 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A2V1AQU0 (Residues: 1-25; Coverage: 10%)
Gene name: CXQ85_001884
Sequence domains: Ribosomal protein L41
Large ribosomal subunit protein eL42 Chain: AP
Molecule details ›
Chain: AP
Length: 106 amino acids
Theoretical weight: 12.29 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PEV4 (Residues: 1-106; Coverage: 100%)
Gene names: CAALFM_C110390CA, RPL42, RPL44, orf19.4909.1
Sequence domains: Ribosomal protein L44
Large ribosomal subunit protein eL43 Chain: AQ
Molecule details ›
Chain: AQ
Length: 92 amino acids
Theoretical weight: 10.14 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PP14 (Residues: 1-92; Coverage: 100%)
Gene names: CAALFM_C504590CA, RPL43A, orf19.3942.1
Sequence domains: Ribosomal L37ae protein family
Ribosome-associated protein STM1 Chain: i
Molecule details ›
Chain: i
Length: 267 amino acids
Theoretical weight: 29.13 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PK71 (Residues: 1-267; Coverage: 100%)
Gene names: CAALFM_C304810CA, STM1, orf19.5943.1
Sequence domains: Stm1
Small ribosomal subunit protein uS2 Chain: B
Molecule details ›
Chain: B
Length: 261 amino acids
Theoretical weight: 28.76 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: O42817 (Residues: 1-261; Coverage: 100%)
Gene names: CAALFM_C305370CA, CaO19.6975, RPS0, YST1
Sequence domains: Ribosomal protein S2
Small ribosomal subunit protein eS1 Chain: C
Molecule details ›
Chain: C
Length: 256 amino acids
Theoretical weight: 29.04 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: P40910 (Residues: 1-256; Coverage: 100%)
Gene names: CAALFM_C103090WA, CaO19.10520, CaO19.3002, PLC1, RP10, RPS1, RPS10
Sequence domains: Ribosomal S3Ae family
Small ribosomal subunit protein uS5 Chain: D
Molecule details ›
Chain: D
Length: 249 amino acids
Theoretical weight: 26.92 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: Q5A900 (Residues: 1-249; Coverage: 100%)
Gene names: CAALFM_C101480CA, RPS2, RPS21, orf19.3334
Sequence domains:
Small ribosomal subunit protein uS3 Chain: E
Molecule details ›
Chain: E
Length: 251 amino acids
Theoretical weight: 27.31 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PSV5 (Residues: 1-251; Coverage: 100%)
Gene names: CAALFM_CR04810WA, RPS3, orf19.6312
Sequence domains:
Small ribosomal subunit protein eS4 Chain: F
Molecule details ›
Chain: F
Length: 262 amino acids
Theoretical weight: 29.44 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PCI6 (Residues: 1-262; Coverage: 100%)
Gene names: CAALFM_C101640WA, RPS42, orf19.3354
Sequence domains:
Small ribosomal subunit protein uS7 Chain: G
Molecule details ›
Chain: G
Length: 225 amino acids
Theoretical weight: 25.32 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: Q5AG43 (Residues: 1-225; Coverage: 100%)
Gene names: CAALFM_C503070WA, RPS5, orf19.4336
Sequence domains: Ribosomal protein S7p/S5e
Small ribosomal subunit protein eS6 Chain: H
Molecule details ›
Chain: H
Length: 236 amino acids
Theoretical weight: 27.15 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PL99 (Residues: 1-236; Coverage: 100%)
Gene names: CAALFM_C401270WA, RPS6A, orf19.4660
Sequence domains: Ribosomal protein S6e
Small ribosomal subunit protein eS7 Chain: I
Molecule details ›
Chain: I
Length: 186 amino acids
Theoretical weight: 21.29 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: Q5AJ93 (Residues: 1-186; Coverage: 100%)
Gene names: CAALFM_C301490WA, RPS7A, orf19.1700
Sequence domains: Ribosomal protein S7e
Small ribosomal subunit protein eS8 Chain: J
Molecule details ›
Chain: J
Length: 206 amino acids
Theoretical weight: 22.8 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: Q59T44 (Residues: 1-206; Coverage: 100%)
Gene names: CAALFM_C205610CA, RPS8A, orf19.6873
Sequence domains: Ribosomal protein S8e
Small ribosomal subunit protein uS4 Chain: K
Molecule details ›
Chain: K
Length: 189 amino acids
Theoretical weight: 21.77 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PGY8 (Residues: 1-189; Coverage: 100%)
Gene names: CAALFM_C203820CA, RPS9B, orf19.838.1
Sequence domains:
Small ribosomal subunit protein eS10 Chain: L
Molecule details ›
Chain: L
Length: 118 amino acids
Theoretical weight: 13.84 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PI15 (Residues: 1-118; Coverage: 100%)
Gene names: CAALFM_C208040CA, RPS10, orf19.2179.2
Sequence domains: Plectin/S10 domain
Small ribosomal subunit protein uS17 Chain: M
Molecule details ›
Chain: M
Length: 155 amino acids
Theoretical weight: 17.64 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PN83 (Residues: 1-155; Coverage: 100%)
Gene names: CAALFM_C501540WA, orf19.4149.1
Sequence domains:
Small ribosomal subunit protein eS12 Chain: N
Molecule details ›
Chain: N
Length: 143 amino acids
Theoretical weight: 15.72 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: Q5ADQ6 (Residues: 1-143; Coverage: 100%)
Gene names: CAALFM_C307150CA, RPS12, orf19.6785
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Small ribosomal subunit protein uS15 Chain: O
Molecule details ›
Chain: O
Length: 151 amino acids
Theoretical weight: 16.98 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PPE0 (Residues: 1-151; Coverage: 100%)
Gene names: CAALFM_C600650CA, RPS13, orf19.4193.1
Sequence domains:
Small ribosomal subunit protein uS11 Chain: P
Molecule details ›
Chain: P
Length: 132 amino acids
Theoretical weight: 14.05 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PDT3 (Residues: 1-132; Coverage: 100%)
Gene names: CAALFM_C106450CA, RPS14B, orf19.6265.1
Sequence domains: Ribosomal protein S11
Small ribosomal subunit protein uS19 Chain: Q
Molecule details ›
Chain: Q
Length: 142 amino acids
Theoretical weight: 15.97 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PK22 (Residues: 1-142; Coverage: 100%)
Gene names: CAALFM_C304670CA, RPS15, orf19.5927
Sequence domains: Ribosomal protein S19
Small ribosomal subunit protein uS9 Chain: R
Molecule details ›
Chain: R
Length: 142 amino acids
Theoretical weight: 15.77 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PCW6 (Residues: 1-142; Coverage: 100%)
Gene names: CAALFM_C103030WA, RPS16A
Sequence domains: Ribosomal protein S9/S16
Small ribosomal subunit protein eS17 Chain: S
Molecule details ›
Chain: S
Length: 137 amino acids
Theoretical weight: 15.77 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PEY9 (Residues: 1-137; Coverage: 100%)
Gene names: CAALFM_C110870WA, RPS17B, orf19.2329.1
Sequence domains: Ribosomal S17
Small ribosomal subunit protein uS13 Chain: T
Molecule details ›
Chain: T
Length: 145 amino acids
Theoretical weight: 17.02 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PQQ5 (Residues: 1-145; Coverage: 100%)
Gene names: CAALFM_C700960WA, RPS18, orf19.7018
Sequence domains: Ribosomal protein S13/S18
Small ribosomal subunit protein eS19 Chain: U
Molecule details ›
Chain: U
Length: 145 amino acids
Theoretical weight: 16.1 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PK61 (Residues: 1-145; Coverage: 100%)
Gene names: CAALFM_C305200WA, RPS19A, orf19.5996.1
Sequence domains: Ribosomal protein S19e
Small ribosomal subunit protein uS10 Chain: V
Molecule details ›
Chain: V
Length: 119 amino acids
Theoretical weight: 13.37 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: Q5A389 (Residues: 1-119; Coverage: 100%)
Gene names: CAALFM_CR08150WA, RPS20, orf19.6375
Sequence domains: Ribosomal protein S10p/S20e
Small ribosomal subunit protein eS21 Chain: W
Molecule details ›
Chain: W
Length: 87 amino acids
Theoretical weight: 9.65 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PCG7 (Residues: 1-87; Coverage: 100%)
Gene names: CAALFM_C101370CA, RPS21B
Sequence domains: Ribosomal protein S21e
Small ribosomal subunit protein uS8A Chain: X
Molecule details ›
Chain: X
Length: 130 amino acids
Theoretical weight: 14.81 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: Q96W54 (Residues: 1-130; Coverage: 100%)
Gene names: CAALFM_C106460CA, CaO19.13644, CaO19.6265, RPS22, RPS22A
Sequence domains: Ribosomal protein S8
Small ribosomal subunit protein uS12 Chain: Y
Molecule details ›
Chain: Y
Length: 145 amino acids
Theoretical weight: 16 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PDU3 (Residues: 1-145; Coverage: 100%)
Gene names: CAALFM_C106580WA, RPS23A, orf19.6253
Sequence domains: Ribosomal protein S12/S23
Small ribosomal subunit protein eS24 Chain: Z
Molecule details ›
Chain: Z
Length: 135 amino acids
Theoretical weight: 15.55 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: Q5A7K0 (Residues: 1-135; Coverage: 100%)
Gene names: CAALFM_C300090WA, RPS24, orf19.5466
Sequence domains: Ribosomal protein S24e
Small ribosomal subunit protein eS25 Chain: a
Molecule details ›
Chain: a
Length: 105 amino acids
Theoretical weight: 11.63 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PNQ6 (Residues: 1-105; Coverage: 100%)
Gene names: CAALFM_C503540CA, RPS25B, orf19.6663
Sequence domains: S25 ribosomal protein
Small ribosomal subunit protein eS26 Chain: b
Molecule details ›
Chain: b
Length: 119 amino acids
Theoretical weight: 13.61 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: Q5ALV6 (Residues: 1-119; Coverage: 100%)
Gene names: CAALFM_C201610CA, RPS26A, orf19.1470
Sequence domains: Ribosomal protein S26e
Small ribosomal subunit protein eS27 Chain: c
Molecule details ›
Chain: c
Length: 82 amino acids
Theoretical weight: 8.98 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PTI7 (Residues: 1-82; Coverage: 100%)
Gene names: CAALFM_CR07630CA, RPS27, orf19.6286.2
Sequence domains: Ribosomal protein S27
Small ribosomal subunit protein eS28 Chain: d
Molecule details ›
Chain: d
Length: 67 amino acids
Theoretical weight: 7.54 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PQN0 (Residues: 1-67; Coverage: 100%)
Gene names: CAALFM_C700710WA, RPS28B, orf19.7048.1
Sequence domains: Ribosomal protein S28e
Small ribosomal subunit protein uS14 Chain: e
Molecule details ›
Chain: e
Length: 56 amino acids
Theoretical weight: 6.62 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PTR4 (Residues: 1-56; Coverage: 100%)
Gene names: CAALFM_CR08480CA, orf19.6415.1
Sequence domains: Ribosomal protein S14p/S29e
Small ribosomal subunit protein eS30 Chain: f
Molecule details ›
Chain: f
Length: 63 amino acids
Theoretical weight: 7.13 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: A0A1D8PSK2 (Residues: 1-63; Coverage: 100%)
Gene names: CAALFM_CR03770CA, RPS30, orf19.4375.1
Sequence domains: Ribosomal protein S30
Ubiquitin-ribosomal protein eS31 fusion protein Chain: g
Molecule details ›
Chain: g
Length: 193 amino acids
Theoretical weight: 22.62 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: Q5A109 (Residues: 1-151; Coverage: 100%)
Gene names: CAALFM_C407180WA, UBI3, orf19.3087
Sequence domains:
Small ribosomal subunit protein RACK1 Chain: h
Molecule details ›
Chain: h
Length: 317 amino acids
Theoretical weight: 34.59 KDa
Source organism: Candida albicans SC5314
UniProt:
  • Canonical: P83774 (Residues: 1-317; Coverage: 100%)
Gene names: ASC1, CAALFM_C701250WA, CaJ7.0140, CaO19.6906
Sequence domains: WD domain, G-beta repeat
25S ribosomal RNA Chain: 1
Molecule details ›
Chain: 1
Length: 3359 nucleotides
Theoretical weight: 1085.31 KDa
Sequence domains: Eukaryotic large subunit ribosomal RNA
5S ribosomal RNA Chain: 3
Molecule details ›
Chain: 3
Length: 121 nucleotides
Theoretical weight: 38.94 KDa
Sequence domains: 5S ribosomal RNA
5.8S ribosomal RNA Chain: 4
Molecule details ›
Chain: 4
Length: 158 nucleotides
Theoretical weight: 50.68 KDa
Sequence domains: 5.8S ribosomal RNA
Mixture of the endogenous E-tRNA Chain: 10
Molecule details ›
Chain: 10
Length: 77 nucleotides
Theoretical weight: 24.73 KDa
Sequence domains: tRNA
18S Ribosomal RNA Chain: A
Molecule details ›
Chain: A
Length: 1787 nucleotides
Theoretical weight: 575.84 KDa
Sequence domains: Eukaryotic small subunit ribosomal RNA

Ligands and Environments

3 bound ligands:
Ligand SPD 2 x SPD
Ligand BLS 1 x BLS
Ligand ZN 8 x ZN
4 modified residues:
Ligand OMG 1 x OMG
Ligand OMC 1 x OMC
Ligand MLZ 3 x MLZ
Ligand IAS 1 x IAS

Experiments and Validation Details

Entry percentile scores
Resolution: 2.67Å
Relevant EMDB volumes: EMD-13750

Quick links

Citations

2 citation in other articles

Imaging-Based Screening Identifies Modulators of the eIF3 Translation Initiation Factor Complex in Candida albicans.
Metzner et al. (2023)
1 more

1 mention without citation

E-site drug specificity of the human pathogen Candida albicans ribosome.
Zgadzay et al. (2022)