› 7q1l

X-ray diffraction
3Å resolution

Glycosilated Human Serum Apo-tranferrin

Released:
DOI: 10.2210/pdb7q1l/pdb
PDB entry 7q1l coloured by chain, front view.
PDB entry 7q1l coloured by chain, side view.
PDB entry 7q1l coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
X-ray Characterization of Conformational Changes of Human Apo- and Holo-Transferrin.
Campos-Escamilla C, Siliqi D, Gonzalez-Ramirez LA, Lopez-Sanchez C, Gavira JA, Moreno A
OpenAccess logo Int J Mol Sci 22 (2021)
PMID: 34948188

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136222 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Serotransferrin Chains: A, B
Molecule details ›
Chains: A, B
Length: 676 amino acids
Theoretical weight: 74.99 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02787 (Residues: 23-698; Coverage: 100%)
Gene names: PRO1400, TF
Sequence domains: Transferrin

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
4 bound ligands:
Ligand GOL 7 x GOL
Ligand EDO 2 x EDO
Ligand MG 1 x MG
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL14-1
Spacegroup: P212121
Unit cell:
a: 87.631Å b: 102.148Å c: 199.969Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.22 0.249

Quick links

Citations

2 citation in other articles

Cisplatin Binding to Human Serum Transferrin: A Crystallographic Study.
Troisi et al. (2023)
1 more

1 mention without citation

X-ray Characterization of Conformational Changes of Human Apo- and Holo-Transferrin.
Campos-Escamilla et al. (2021)