› 7q3h

Electron Microscopy
3.2Å resolution

Pentameric ligand-gated ion channel, DeCLIC at pH 7 with 10 mM EDTA

Released:
DOI: 10.2210/pdb7q3h/pdb
PDB entry 7q3h coloured by chain, front view.
PDB entry 7q3h coloured by chain, side view.
PDB entry 7q3h coloured by chain, top view.
Source organism: Desulfofustis sp. PB-SRB1
Primary publication:
Biophysical characterization of calcium-binding and modulatory-domain dynamics in a pentameric ligand-gated ion channel.
Lycksell M, Rovšnik U, Hanke A, Martel A, Howard RJ, Lindahl E
OpenAccess logo Proc Natl Acad Sci U S A 119 e2210669119 (2022)
PMID: 36480474
Related structures: EMD-13792

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-197598 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neur_chan_LBD domain-containing protein Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 642 amino acids
Theoretical weight: 71.73 KDa
Source organism: Desulfofustis sp. PB-SRB1
Expression system: Escherichia coli
UniProt:
  • Canonical: V4JF97 (Residues: 1-642; Coverage: 100%)
Gene name: JKP90_15375
Sequence domains: Neurotransmitter-gated ion-channel ligand binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.2Å
Relevant EMDB volumes: EMD-13792
Expression system: Escherichia coli

Quick links

Citations

1 mention without citation

Biophysical characterization of calcium-binding and modulatory-domain dynamics in a pentameric ligand-gated ion channel.
Lycksell et al. (2022)