7qj3

Electron Microscopy
7.6Å resolution

Structure of recombinant human gamma-Tubulin Ring Complex 8-spoked assembly intermediate (spokes 7-14)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 22-mer (preferred)
PDBe Complex ID:
PDB-CPX-149918 (preferred)
Entry contents:
7 distinct polypeptide molecules
Macromolecules (7 distinct):
Tubulin gamma-1 chain Chains: 1, 2, U, V, W, X, Y, Z
Molecule details ›
Chains: 1, 2, U, V, W, X, Y, Z
Length: 451 amino acids
Theoretical weight: 51.23 KDa
Source organism: Homo sapiens
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017
UniProt:
  • Canonical: P23258 (Residues: 1-451; Coverage: 100%)
Gene names: TUBG, TUBG1
Sequence domains:
Mitotic-spindle organizing protein 1 Chains: b, m, o
Molecule details ›
Chains: b, m, o
Length: 82 amino acids
Theoretical weight: 8.49 KDa
Source organism: Homo sapiens
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017
UniProt:
  • Canonical: Q08AG7 (Residues: 1-82; Coverage: 100%)
Gene names: C13orf37, MOZART1, MZT1
Sequence domains: Mitotic-spindle organizing gamma-tubulin ring associated
Gamma-tubulin complex component 3 Chains: H, N, a, n
Molecule details ›
Chains: H, N, a, n
Length: 907 amino acids
Theoretical weight: 103.71 KDa
Source organism: Homo sapiens
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017
UniProt:
  • Canonical: Q96CW5 (Residues: 1-907; Coverage: 100%)
Gene names: GCP3, TUBGCP3
Sequence domains:
Gamma-tubulin complex component 5 Chains: J, l
Molecule details ›
Chains: J, l
Length: 1024 amino acids
Theoretical weight: 118.47 KDa
Source organism: Homo sapiens
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017
UniProt:
  • Canonical: Q96RT8 (Residues: 1-1024; Coverage: 100%)
Gene names: GCP5, KIAA1899, TUBGCP5
Sequence domains:
Gamma-tubulin complex component 2 Chains: G, M
Molecule details ›
Chains: G, M
Length: 902 amino acids
Theoretical weight: 102.67 KDa
Source organism: Homo sapiens
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017
UniProt:
  • Canonical: Q9BSJ2 (Residues: 1-902; Coverage: 100%)
Gene names: GCP2, TUBGCP2
Sequence domains:
Gamma-tubulin complex component 4 Chains: I, K
Molecule details ›
Chains: I, K
Length: 667 amino acids
Theoretical weight: 76.18 KDa
Source organism: Homo sapiens
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017
UniProt:
  • Canonical: Q9UGJ1 (Residues: 1-667; Coverage: 100%)
Gene names: 76P, GCP4, TUBGCP4
Sequence domains:
Gamma-tubulin complex component 6 Chain: L
Molecule details ›
Chain: L
Length: 1819 amino acids
Theoretical weight: 200.73 KDa
Source organism: Homo sapiens
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017
UniProt:
  • Canonical: Q96RT7 (Residues: 1-1819; Coverage: 100%)
Gene names: GCP6, KIAA1669, TUBGCP6
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 7.6Å
Relevant EMDB volumes: EMD-14008
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017