Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Neurotransmitter-gated ion-channel
- Nicotinic acetylcholine receptor
- Neuronal acetylcholine receptor
- Neurotransmitter-gated ion-channel ligand-binding domain superfamily
- Neurotransmitter-gated ion-channel transmembrane domain
- Neurotransmitter-gated ion-channel transmembrane domain superfamily
- Neurotransmitter-gated ion-channel, conserved site
- Neurotransmitter-gated ion-channel ligand-binding domain
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
Assembly name:
Acetylcholine receptor, alpha1-beta1-gamma-delta (preferred)
PDBe Complex ID:
PDB-CPX-136090 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (8 distinct):
Acetylcholine receptor subunit alpha
Molecule details ›
Chains: A, D
Length: 437 amino acids
Theoretical weight: 50.17 KDa
Source organism: Tetronarce californica
UniProt:
Sequence domains:
Length: 437 amino acids
Theoretical weight: 50.17 KDa
Source organism: Tetronarce californica
UniProt:
- Canonical:
P02710 (Residues: 25-461; Coverage: 100%)
Sequence domains:
Acetylcholine receptor subunit beta
Molecule details ›
Chain: B
Length: 469 amino acids
Theoretical weight: 53.73 KDa
Source organism: Tetronarce californica
UniProt:
Sequence domains:
Length: 469 amino acids
Theoretical weight: 53.73 KDa
Source organism: Tetronarce californica
UniProt:
- Canonical: P02712 (Residues: 25-493; Coverage: 100%)
Sequence domains:
Acetylcholine receptor subunit delta
Molecule details ›
Chain: C
Length: 501 amino acids
Theoretical weight: 57.63 KDa
Source organism: Tetronarce californica
UniProt:
Sequence domains:
Length: 501 amino acids
Theoretical weight: 57.63 KDa
Source organism: Tetronarce californica
UniProt:
- Canonical: P02718 (Residues: 22-522; Coverage: 100%)
Sequence domains:
Acetylcholine receptor subunit gamma
Molecule details ›
Chain: E
Length: 489 amino acids
Theoretical weight: 56.34 KDa
Source organism: Tetronarce californica
UniProt:
Sequence domains:
Length: 489 amino acids
Theoretical weight: 56.34 KDa
Source organism: Tetronarce californica
UniProt:
- Canonical: P02714 (Residues: 18-506; Coverage: 100%)
Sequence domains:
Ligands and Environments
1 bound ligand:
No modified residues
