7qto

X-ray diffraction
3.5Å resolution

Structural biology of the NS1 avian influenza protein subversion on the Scribble cell polarity module

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-171947 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein scribble homolog Chains: A, B
Molecule details ›
Chains: A, B
Length: 117 amino acids
Theoretical weight: 12.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14160 (Residues: 700-816; Coverage: 7%)
Gene names: CRIB1, KIAA0147, LAP4, SCRB1, SCRIB, VARTUL
Sequence domains: PDZ domain
Non-structural protein 1 Chains: C, D
Molecule details ›
Chains: C, D
Length: 8 amino acids
Theoretical weight: 905 Da
Source organism: H5N1 subtype
Expression system: Not provided
UniProt:
  • Canonical: Q6DP93 (Residues: 218-225; Coverage: 4%)
Gene name: NS

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Unit cell:
a: 56.909Å b: 57.009Å c: 61.598Å
α: 90° β: 117.372° γ: 90°
R-values:
R R work R free
0.244 0.242 0.266
Expression systems:
  • Escherichia coli
  • Not provided