Protein Data Bank in Europe

Chain: A
Length: 1132 amino acids
Theoretical weight: 127.2 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:

• Canonical: O14746 (Residues: 1-1132; Coverage: 100%)

Gene names: EST2, TCS1, TERT, TRT
Sequence domains:

• Telomerase ribonucleoprotein complex - RNA binding domain
• Reverse transcriptase (RNA-dependent DNA polymerase)
• Telomerase reverse transcriptase, C-terminal extension

Chain: L
Length: 130 amino acids
Theoretical weight: 14.14 KDa
Source organism: Homo sapiens
UniProt:

• Canonical: B2R5B3 (Residues: 1-130; Coverage: 100%)

Sequence domains:

• Core histone H2A/H2B/H3/H4
• C-terminus of histone H2A

Chain: M
Length: 166 amino acids
Theoretical weight: 18.07 KDa
Source organism: Homo sapiens
UniProt:

• Canonical: B4DR52 (Residues: 1-166; Coverage: 100%)

Sequence domains: Core histone H2A/H2B/H3/H4

Chain: O
Length: 458 amino acids
Theoretical weight: 49.01 KDa
Source organism: Homo sapiens
Expression system: Spodoptera
UniProt:

• Canonical: Q96AP0 (Residues: 1-458; Coverage: 100%)

Gene names: ACD, PIP1, PTOP, TINT1, TPP1
Sequence domains: Shelterin complex subunit, TPP1/ACD

Chain: P
Length: 634 amino acids
Theoretical weight: 71.52 KDa
Source organism: Homo sapiens
Expression system: Spodoptera
UniProt:

• Canonical: Q9NUX5 (Residues: 1-634; Coverage: 100%)

Gene name: POT1
Sequence domains:

• Telomeric single stranded DNA binding POT1/CDC13
• ssDNA-binding domain of telomere protection protein
• Protection of telomeres protein 1 (POT1), C-terminal insertion domain

Chain: N
Length: 30 nucleotides
Theoretical weight: 9.5 KDa

Chain: B
Length: 451 nucleotides
Theoretical weight: 145.48 KDa
Sequence domains: Vertebrate telomerase RNA