› 7qzm

X-ray diffraction
1.45Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180199 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATPase family AAA domain-containing protein 2 Chain: AAA
Molecule details ›
Chain: AAA
Length: 130 amino acids
Theoretical weight: 15.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6PL18 (Residues: 981-1108; Coverage: 9%)
Gene names: ATAD2, L16, PRO2000
Sequence domains: Bromodomain

Ligands and Environments

4 bound ligands:
Ligand SO4 2 x SO4
Ligand CL 1 x CL
Ligand EDO 8 x EDO
Ligand UUS 1 x UUS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P6522
Unit cell:
a: 79.068Å b: 79.068Å c: 137.07Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.209 0.208 0.242
Expression system: Escherichia coli

Quick links

Citations

1 citations in other articles

Fragment expansion with NUDELs - poised DNA-encoded libraries.
Salvini et al. (2023)

1 mention without citation

Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions.
Davison et al. (2022)