› 7qzo

X-ray diffraction
1.45Å resolution

Function and Biology Details

Reaction catalysed: 
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine
Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-124414 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
histidine kinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 156 amino acids
Theoretical weight: 17.29 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: G3XD98 (Residues: 662-793; Coverage: 14%)
Gene names: PA0928, gacS
Sequence domains: Response regulator receiver domain

Ligands and Environments

2 bound ligands:
Ligand CD 5 x CD
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 2
Spacegroup: C2221
Unit cell:
a: 69.152Å b: 73.532Å c: 104.348Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.132 0.131 0.154
Expression system: Escherichia coli BL21

Quick links

Citations

1 review citation

Transcriptional Regulators Controlling Virulence in Pseudomonas aeruginosa.
Sánchez-Jiménez et al. (2023)