› 7raq

X-ray diffraction
1.74Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-209903 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
CV3-25 Fab Heavy Chain Chain: H
Molecule details ›
Chain: H
Length: 232 amino acids
Theoretical weight: 25.03 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
CV3-25 Fab Light Chain Chain: L
Molecule details ›
Chain: L
Length: 214 amino acids
Theoretical weight: 23.22 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Spike protein S2' Chain: P
Molecule details ›
Chain: P
Length: 19 amino acids
Theoretical weight: 2.24 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Not provided
UniProt:
  • Canonical: P0DTC2 (Residues: 1149-1167; Coverage: 2%)
Gene names: 2, S

Ligands and Environments

2 bound ligands:
Ligand GOL 7 x GOL
Ligand SO4 2 x SO4
1 modified residue:
Ligand PCA 1 x PCA

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P3221
Unit cell:
a: 60.173Å b: 60.173Å c: 285.825Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.182 0.181 0.203
Expression systems:
  • Homo sapiens
  • Not provided

Quick links

Citations

8 review citations

Monoclonal antibody therapies against SARS-CoV-2.
Focosi et al. (2022)
7 more

2 mentions without citation

SARS-CoV-2 spike S2-specific neutralizing antibodies.
Li et al. (2023)
1 more