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Crystal Structure of ADP-bound Galactokinase

Source organism: Homo sapiens
Biochemical function: phosphotransferase activity, alcohol group as acceptor
Biological process: glycolytic process from galactose
Cellular component: extracellular exosome

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EC 2.7.1.6: Galactokinase

Reaction catalysed:
ATP + alpha-D-galactose = ADP + alpha-D-galactose 1-phosphate
Systematic name:
ATP:alpha-D-galactose 1-phosphotransferase
Alternative Name(s):
  • ATP:D-galactose-1-phosphotransferase
  • Galactokinase (phosphorylating)

GO terms

Sequence families

Pfam Protein families (Pfam)
PF08544
Domain description: GHMP kinases C terminal
Occurring in:
  1. Galactokinase
The deposited structure of PDB entry 7rcm contains 2 copies of Pfam domain PF08544 (GHMP kinases C terminal ) in Galactokinase. Showing 1 copy in chain A.

PF00288
Domain description: GHMP kinases N terminal domain
Occurring in:
  1. Galactokinase
The deposited structure of PDB entry 7rcm contains 2 copies of Pfam domain PF00288 (GHMP kinases N terminal domain) in Galactokinase. Showing 1 copy in chain A.

PF10509
Domain description: Galactokinase galactose-binding signature
Occurring in:
  1. Galactokinase
The deposited structure of PDB entry 7rcm contains 2 copies of Pfam domain PF10509 (Galactokinase galactose-binding signature) in Galactokinase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000705
Domain description: Galactokinase
Occurring in:
  1. Galactokinase
IPR036554
Domain description: GHMP kinase, C-terminal domain superfamily
Occurring in:
  1. Galactokinase
IPR013750
Domain description: GHMP kinase, C-terminal domain
Occurring in:
  1. Galactokinase
IPR006203
Domain description: GHMP kinase, ATP-binding, conserved site
Occurring in:
  1. Galactokinase
IPR006204
Domain description: GHMP kinase N-terminal domain
Occurring in:
  1. Galactokinase
IPR019741
Domain description: Galactokinase, conserved site
Occurring in:
  1. Galactokinase
IPR019539
Domain description: Galactokinase, N-terminal domain
Occurring in:
  1. Galactokinase
IPR020568
Domain description: Ribosomal protein uS5 domain 2-type superfamily
Occurring in:
  1. Galactokinase
IPR014721
Domain description: Small ribosomal subunit protein uS5 domain 2-type fold, subgroup
Occurring in:
  1. Galactokinase
IPR006206
Domain description: Mevalonate/galactokinase
Occurring in:
  1. Galactokinase

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