› 7rda

X-ray diffraction
1.92Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-208855 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Circumsporozoite protein Chain: C
Molecule details ›
Chain: C
Length: 15 amino acids
Theoretical weight: 1.56 KDa
Source organism: Plasmodium falciparum
Expression system: Not provided
UniProt:
  • Canonical: P02893 (Residues: 120-134; Coverage: 4%)
Gene name: CSP
antibody m43.138 heavy chain Chain: H
Molecule details ›
Chain: H
Length: 255 amino acids
Theoretical weight: 27.32 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
antibody m43.138 light chain Chain: L
Molecule details ›
Chain: L
Length: 220 amino acids
Theoretical weight: 24.16 KDa
Source organism: Mus musculus
Expression system: Homo sapiens

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P212121
Unit cell:
a: 60.492Å b: 79.263Å c: 90.922Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.198 0.232
Expression systems:
  • Not provided
  • Homo sapiens

Quick links

Citations

2 review citations

Progress in building clinically relevant patient-derived tumor xenograft models for cancer research.
Wang et al. (2023)
1 more

1 mention without citation

Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Kratochvil et al. (2021)