› 7rdn

X-ray diffraction
2.49Å resolution

Crystal structure of S. cerevisiae pre-mRNA leakage protein 39 (Pml39)

Released:
DOI: 10.2210/pdb7rdn/pdb
PDB entry 7rdn coloured by chain, front view.
PDB entry 7rdn coloured by chain, side view.
PDB entry 7rdn coloured by chain, top view.
Source organism: Saccharomyces cerevisiae S288C
Primary publication:
Structure of the pre-mRNA leakage 39-kDa protein reveals a single domain of integrated zf-C3HC and Rsm1 modules.
Hashimoto H, Ramirez DH, Lautier O, Pawlak N, Blobel G, Palancade B, Debler EW
OpenAccess logo Sci Rep 12 17691 (2022)
PMID: 36271106

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-554467 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pre-mRNA leakage protein 39 Chain: A
Molecule details ›
Chain: A
Length: 247 amino acids
Theoretical weight: 29.09 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
  • Canonical: Q03760 (Residues: 77-317; Coverage: 72%)
Gene names: PML39, YM8339.12, YML107C
Sequence domains: C3HC zinc finger-like

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P3121
Unit cell:
a: 53.01Å b: 53.01Å c: 171.27Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.234 0.233 0.262
Expression system: Escherichia coli

Quick links

Citations

1 citations in other articles

An evolutionarily conserved bimodular domain anchors ZC3HC1 and its yeast homologue Pml39p to the nuclear basket.
Gunkel et al. (2023)

1 mention without citation

Structure of the pre-mRNA leakage 39-kDa protein reveals a single domain of integrated zf-C3HC and Rsm1 modules.
Hashimoto et al. (2022)