7rit

Electron Microscopy
5.2Å resolution

Drug-free A. baumannii MsbA

Released:
Source organism: Acinetobacter baumannii
Primary publication:
Distinct allosteric mechanisms of first-generation MsbA inhibitors.
Science 374 580-585 (2021)
PMID: 34554829
Related structures: EMD-23804

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-101039 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lipid A export permease/ATP-binding protein MsbA Chains: A, B
Molecule details ›
Chains: A, B
Length: 607 amino acids
Theoretical weight: 67.76 KDa
Source organism: Acinetobacter baumannii
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0B9X4I2 (Residues: 2-575; Coverage: 100%)
Gene names: APD33_16495, B9X95_12125, DOL94_12040, IMO23_08005, msbA
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 5.2Å
Relevant EMDB volumes: EMD-23804
Expression system: Escherichia coli