› 7rkf

Electron Microscopy
4Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-211006 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (6 distinct):
Guanine nucleotide-binding protein subunit alpha-11 Chain: A
Molecule details ›
Chain: A
Length: 352 amino acids
Theoretical weight: 41.25 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P29992 (Residues: 25-359; Coverage: 93%)
Gene names: GA11, GNA11
Sequence domains: G-protein alpha subunit
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Chain: B
Molecule details ›
Chain: B
Length: 345 amino acids
Theoretical weight: 37.73 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P62873 (Residues: 2-340; Coverage: 100%)
Gene name: GNB1
Sequence domains: WD domain, G-beta repeat
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Chain: C
Molecule details ›
Chain: C
Length: 67 amino acids
Theoretical weight: 7.43 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P59768 (Residues: 2-68; Coverage: 94%)
Gene name: GNG2
Sequence domains: GGL domain
Antibody fragment scFv16 Chain: D
Molecule details ›
Chain: D
Length: 256 amino acids
Theoretical weight: 27.34 KDa
Source organism: Mus musculus
Expression system: Trichoplusia ni
Processed fractalkine Chain: L
Molecule details ›
Chain: L
Length: 91 amino acids
Theoretical weight: 10.01 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P78423 (Residues: 25-101; Coverage: 21%)
Gene names: A-152E5.2, CX3CL1, FKN, NTT, SCYD1
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
G-protein coupled receptor homolog US28 Chain: R
Molecule details ›
Chain: R
Length: 362 amino acids
Theoretical weight: 42.04 KDa
Source organism: Human betaherpesvirus 5
Expression system: Homo sapiens
UniProt:
  • Canonical: P69332 (Residues: 1-354; Coverage: 100%)
Gene name: US28
Sequence domains: 7 transmembrane receptor (rhodopsin family)

Ligands and Environments

2 bound ligands:
Ligand GDP 1 x GDP
Ligand NAG 1 x NAG
1 modified residue:
Ligand PCA 1 x PCA

Experiments and Validation Details

Entry percentile scores
Resolution: 4Å
Relevant EMDB volumes: EMD-24496
Expression systems:
  • Trichoplusia ni
  • Homo sapiens

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