› 7rq6

Electron Microscopy
4.18Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-225365 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1246 amino acids
Theoretical weight: 138.02 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-1208; Coverage: 95%)
Gene names: 2, S
Sequence domains:
CV3-13 Fab heavy chain Chains: D, H, J
Molecule details ›
Chains: D, H, J
Length: 225 amino acids
Theoretical weight: 24.08 KDa
Source organism: Homo sapiens
CV3-13 Fab light chain Chains: E, K, L
Molecule details ›
Chains: E, K, L
Length: 212 amino acids
Theoretical weight: 23.32 KDa
Source organism: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand NAG 36 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.18Å
Relevant EMDB volumes: EMD-24628
Expression system: Homo sapiens

Quick links

Citations

10 review citations

Molecular characteristics, immune evasion, and impact of SARS-CoV-2 variants.
Sun et al. (2022)
9 more

2 mentions without citation

A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection.
Beaudoin-Bussières et al. (2022)
1 more