› 7rr9

Electron Microscopy
3.5Å resolution

Cryo-EM Structure of Nanodisc reconstituted ABCD1 in nucleotide bound outward open conformation

Released:
DOI: 10.2210/pdb7rr9/pdb
PDB entry 7rr9 coloured by chain, front view.
PDB entry 7rr9 coloured by chain, side view.
PDB entry 7rr9 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structures of the human peroxisomal fatty acid transporter ABCD1 in a lipid environment
Le LTM, Thompson JR, Dang PX, Bhandari J, Alam A
Commun Biol 5 7- (2022)
Related structures: EMD-24656

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152660 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-binding cassette sub-family D member 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 745 amino acids
Theoretical weight: 83.04 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P33897 (Residues: 1-745; Coverage: 100%)
Gene names: ABCD1, ALD
Sequence domains:

Ligands and Environments

4 bound ligands:
Ligand UNL 2 x UNL
Ligand CLR 2 x CLR
Ligand MG 2 x MG
Ligand AGS 2 x AGS
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-24656
Expression system: Homo sapiens

Quick links