› 7rwr

Solution NMR

An RNA aptamer that decreases flavin redox potential

Released:
DOI: 10.2210/pdb7rwr/pdb
PDB entry 7rwr coloured by chain, ensemble of 10 models, front view.
PDB entry 7rwr coloured by chain, ensemble of 10 models, side view.
PDB entry 7rwr coloured by chain, ensemble of 10 models, top view.
Source organism: synthetic construct
Primary publication:
An RNA aptamer that shifts the reduction potential of metabolic cofactors.
Samuelian JS, Gremminger TJ, Song Z, Poudyal RR, Li J, Zhou Y, Staller SA, Carballo JA, Roychowdhury-Saha M, Chen SJ, Burke DH, Heng X, Baum DA
OpenAccess logo Nat Chem Biol (2022)
PMID: 36097297

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-197324 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA (38-MER) Chain: A
Molecule details ›
Chain: A
Length: 38 nucleotides
Theoretical weight: 12.23 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand FMN 1 x FMN
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 22%
Refinement method: molecular dynamics
Expression system: Not provided

Quick links

Citations

1 review citation

Biological Catalysis and Information Storage Have Relied on N-Glycosyl Derivatives of β-D-Ribofuranose since the Origins of Life.
Wozniak et al. (2023)
3 other articles