› 7rwt

Electron Microscopy
2.43Å resolution

Adeno-associated virus type 2

Released:
DOI: 10.2210/pdb7rwt/pdb
PDB entry 7rwt coloured by chain, front view.
PDB entry 7rwt coloured by chain, side view.
PDB entry 7rwt coloured by chain, top view.
Source organism: Adeno-associated dependoparvovirus A
Primary publication:
Structural characterization of an envelope-associated adeno-associated virus type 2 capsid.
Hull JA, Mietzsch M, Chipman P, Strugatsky D, McKenna R
Virology 565 22-28 (2022)
PMID: 34638006
Related structures: EMD-24719

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo 60-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136598 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsid protein VP1 Chains: 1, 2, 3, 4, 5, 6, 7, 8, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d, e, f, g, h, i, j, k, l, m, n, o, p, q, r, s, t, u, v, w, x, y, z
Molecule details ›
Chains: 1, 2, 3, 4, 5, 6, 7, 8, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d, e, f, g, h, i, j, k, l, m, n, o, p, q, r, s, t, u, v, w, x, y, z
Length: 735 amino acids
Theoretical weight: 82.03 KDa
Source organism: Adeno-associated dependoparvovirus A
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P03135 (Residues: 1-735; Coverage: 100%)
Gene name: VP1
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.43Å
Relevant EMDB volumes: EMD-24719
Expression system: Spodoptera frugiperda

Quick links

Citations

2 citation in other articles

An adeno-associated virus variant enabling efficient ocular-directed gene delivery across species.
Luo et al. (2024)
1 more

1 mention without citation

Structural characterization of an envelope-associated adeno-associated virus type 2 capsid.
Hull et al. (2022)