afTMEM16 in C14 lipid nanodiscs with MSP1E3 scaffold protein in the absence of Ca2+
Source organism:
Aspergillus fumigatus A1163
Biochemical function:
phospholipid scramblase activity
Biological process: chloride transmembrane transport
Cellular component: cortical endoplasmic reticulum
Biological process: chloride transmembrane transport
Cellular component: cortical endoplasmic reticulum
Protein families (Pfam)![The deposited structure of PDB entry 7rx3 contains 2 copies of Pfam domain PF04547 (Calcium-activated chloride channel) in Plasma membrane channel protein (Aqy1). Showing 1 copy in chain B [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/7rx3_1_A_Pfam_PF04547_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>7rx3</span> contains 2 copies of Pfam domain <span class='highlight'>PF04547 (Calcium-activated chloride channel)</span> in <span class='highlight'>Plasma membrane channel protein (Aqy1)</span>. Showing 1 copy in chain <span class='highlight'>B [auth A]</span>.")
![The deposited structure of PDB entry 7rx3 contains 2 copies of Pfam domain PF20877 (Alpha-beta plait domain in TMEM16 lipid scramblase) in Plasma membrane channel protein (Aqy1). Showing 1 copy in chain B [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/7rx3_1_A_Pfam_PF20877_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>7rx3</span> contains 2 copies of Pfam domain <span class='highlight'>PF20877 (Alpha-beta plait domain in TMEM16 lipid scramblase)</span> in <span class='highlight'>Plasma membrane channel protein (Aqy1)</span>. Showing 1 copy in chain <span class='highlight'>B [auth A]</span>.")
InterPro annotation