Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138932 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Insulin-like growth factor 1 receptor alpha chain
Molecule details ›
Chain: A
Length: 952 amino acids
Theoretical weight: 108.94 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
Sequence domains:
Length: 952 amino acids
Theoretical weight: 108.94 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
- Canonical:
P08069 (Residues: 31-935; Coverage: 68%)
Sequence domains:
Insulin receptor subunit alpha
Molecule details ›
Chain: B
Length: 961 amino acids
Theoretical weight: 109.81 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
Sequence domains:
Length: 961 amino acids
Theoretical weight: 109.81 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
- Canonical: P06213 (Residues: 28-955; Coverage: 69%)
Sequence domains:
