› 7s9z

Electron Microscopy
4.14Å resolution

Helicobacter Hepaticus CcsBA Closed Conformation

Released:
DOI: 10.2210/pdb7s9z/pdb
PDB entry 7s9z coloured by chain, front view.
PDB entry 7s9z coloured by chain, side view.
PDB entry 7s9z coloured by chain, top view.
Source organism: Helicobacter hepaticus
Primary publication:
Cryo-EM of CcsBA reveals the basis for cytochrome c biogenesis and heme transport.
Mendez DL, Lowder EP, Tillman DE, Sutherland MC, Collier AL, Rau MJ, Fitzpatrick JAJ, Kranz RG
OpenAccess logo Nat Chem Biol 18 101-108 (2022)
PMID: 34931065
Related structures: EMD-24942

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182062 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytochrome c biogenesis protein Chain: A
Molecule details ›
Chain: A
Length: 942 amino acids
Theoretical weight: 107.29 KDa
Source organism: Helicobacter hepaticus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q7VHG9 (Residues: 1-936; Coverage: 100%)
Gene name: HH_0998
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand PTY 1 x PTY
Ligand HEB 1 x HEB
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.14Å
Relevant EMDB volumes: EMD-24942
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Cytoprotective Role of Heme Oxygenase-1 in Cancer Chemoresistance: Focus on Antioxidant, Antiapoptotic, and Pro-Autophagy Properties.
Wang et al. (2023)
7 other articles

4 mentions without citation

Cryo-EM of CcsBA reveals the basis for cytochrome c biogenesis and heme transport.
Mendez et al. (2022)
3 more