› 7sc0

Electron Microscopy
3.4Å resolution

CryoEM structure of the Caveolin-1 8S complex

Released:
DOI: 10.2210/pdb7sc0/pdb
PDB entry 7sc0 coloured by chain, front view.
PDB entry 7sc0 coloured by chain, side view.
PDB entry 7sc0 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Molecular architecture of the human caveolin-1 complex.
Porta JC, Han B, Gulsevin A, Chung JM, Peskova Y, Connolly S, Mchaourab HS, Meiler J, Karakas E, Kenworthy AK, Ohi MD
OpenAccess logo Sci Adv 8 eabn7232 (2022)
PMID: 35544577
Related structures: EMD-25007

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo undecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169845 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Caveolin-1 Chains: A, B, C, D, E, F, G, H, I, J, K
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K
Length: 178 amino acids
Theoretical weight: 20.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q03135 (Residues: 1-178; Coverage: 100%)
Gene names: CAV, CAV1
Sequence domains: Caveolin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.4Å
Relevant EMDB volumes: EMD-25007
Expression system: Escherichia coli BL21

Quick links

Citations

6 review citations

Emerging Insights into the Molecular Architecture of Caveolin-1.
Ohi et al. (2022)
5 more

7 mentions without citation

Molecular Mechanism and Role of Japanese Encephalitis Virus Infection in Central Nervous System-Mediated Diseases.
Yadav et al. (2022)
6 more