› 7sdb

X-ray diffraction
2Å resolution

Structure of the PTP-like myo-inositol phosphatase from Legionella pneumophila str. Paris in complex with myo-inositol hexakisphosphate

Released:
DOI: 10.2210/pdb7sdb/pdb
PDB entry 7sdb coloured by chain, front view.
PDB entry 7sdb coloured by chain, side view.
PDB entry 7sdb coloured by chain, top view.
Source organism: Legionella pneumophila str. Paris
Entry authors: Cleland CP, Mosimann SC

Function and Biology Details

Reaction catalysed: 
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-217084 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine phosphatase II superfamily protein Chain: A
Molecule details ›
Chain: A
Length: 314 amino acids
Theoretical weight: 36.03 KDa
Source organism: Legionella pneumophila str. Paris
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5ZRR1 (Residues: 21-319; Coverage: 100%)
Gene name: lpg2819
Sequence domains: Inositol hexakisphosphate

Ligands and Environments

1 bound ligand:
Ligand IHP 1 x IHP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-003
Spacegroup: P212121
Unit cell:
a: 62.309Å b: 62.456Å c: 95.497Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.167 0.164 0.196
Expression system: Escherichia coli BL21(DE3)

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