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Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 5(delta dII)

Electron Microscopy
4.2Å resolution
PDB entry 7syk coloured by chain, front view.
PDB entry 7syk coloured by chain, side view.
PDB entry 7syk coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Assembly composition:
hetero 36-mer (preferred)
Entry contents: 34 distinct polypeptide molecules
2 distinct RNA molecules

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Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero 36-mer
Accessible surface area: 448848.26 Å2
Buried surface area: 188990.33 Å2
Dissociation area: 1,859.65 Å2
Dissociation energy (ΔGdiss): 0.09 kcal/mol
Dissociation entropy (TΔSdiss): 14.91 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-239226

Macromolecules

Small ribosomal subunit protein uS2
Chain: B
Length: 295 amino acids
Theoretical weight: 32.96 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TLT8 (Residues: 1-295; Coverage: 100%)
Gene name: RPSA
Pfam:
InterPro:
Small ribosomal subunit protein uS2 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein uS2 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein uS2 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1TLT8  
129520406080100120140160180200220240260280
 
100200
UniProt
G1TLT8
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Small ribosomal subunit protein eS1
Chain: C
Length: 264 amino acids
Theoretical weight: 30 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SS70 (Residues: 1-264; Coverage: 100%)
Gene name: RPS3A
Pfam: Ribosomal S3Ae family
InterPro:
Small ribosomal subunit protein eS1 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein eS1 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein eS1 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1SS70  
126420406080100120140160180200220240260
 
100200
UniProt
G1SS70
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Large ribosomal subunit protein uL30
Chain: D
Length: 221 amino acids
Theoretical weight: 24.44 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SV32 (Residues: 155-192; Coverage: 18%)
Gene name: RPL7
InterPro:
Large ribosomal subunit protein uL30 in PDB entry 7syk, assembly 1, front view.
Large ribosomal subunit protein uL30 in PDB entry 7syk, assembly 1, side view.
Large ribosomal subunit protein uL30 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1SV32  
122120406080100120140160180200220
 
100200
UniProt
G1SV32
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Small ribosomal subunit protein uS3
Chain: E
Length: 281 amino acids
Theoretical weight: 31.15 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TNM3 (Residues: 1-243; Coverage: 100%)
Gene name: RPS3
Pfam:
InterPro:
Small ribosomal subunit protein uS3 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein uS3 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein uS3 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1TNM3  
128120406080100120140160180200220240260280
 
100200
UniProt
G1TNM3
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40S ribosomal protein S4
Chain: F
Length: 263 amino acids
Theoretical weight: 29.65 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TA47 (Residues: 1-263; Coverage: 100%)
Pfam:
InterPro:
40S ribosomal protein S4 in PDB entry 7syk, assembly 1, front view.
40S ribosomal protein S4 in PDB entry 7syk, assembly 1, side view.
40S ribosomal protein S4 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1TA47  
126320406080100120140160180200220240260
 
100200
UniProt
G1TA47
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Small ribosomal subunit protein uS7
Chain: G
Length: 204 amino acids
Theoretical weight: 22.91 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TFM5 (Residues: 1-204; Coverage: 100%)
Gene name: RPS5
Pfam: Ribosomal protein S7p/S5e
InterPro:
Small ribosomal subunit protein uS7 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein uS7 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein uS7 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1TFM5  
120420406080100120140160180200
 
50100150200
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G1TFM5
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40S ribosomal protein S6
Chain: H
Length: 249 amino acids
Theoretical weight: 28.75 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A5K1UJS7 (Residues: 1-249; Coverage: 100%)
Pfam: Ribosomal protein S6e
InterPro:
40S ribosomal protein S6 in PDB entry 7syk, assembly 1, front view.
40S ribosomal protein S6 in PDB entry 7syk, assembly 1, side view.
40S ribosomal protein S6 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: A0A5K1UJS7  
124920406080100120140160180200220240
 
100200
UniProt
A0A5K1UJS7
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Small ribosomal subunit protein eS7
Chain: I
Length: 432 amino acids
Theoretical weight: 47.36 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SVB0 (Residues: 1-194; Coverage: 100%)
Gene name: RPS7
InterPro:
Small ribosomal subunit protein eS7 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein eS7 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein eS7 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1SVB0  
143250100150200250300350400
 
200400
UniProt
G1SVB0
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Small ribosomal subunit protein eS8
Chain: J
Length: 208 amino acids
Theoretical weight: 24.26 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TJW1 (Residues: 1-208; Coverage: 100%)
Gene name: RPS8
Pfam: Ribosomal protein S8e
InterPro:
Small ribosomal subunit protein eS8 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein eS8 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein eS8 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1TJW1  
120820406080100120140160180200
 
50100150200
UniProt
G1TJW1
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Small ribosomal subunit protein uS4
Chain: K
Length: 194 amino acids
Theoretical weight: 22.64 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: B7NZS8 (Residues: 1-194; Coverage: 100%)
Gene name: RPS9
Pfam:
InterPro:
Small ribosomal subunit protein uS4 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein uS4 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein uS4 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: B7NZS8  
119420406080100120140160180
 
50100150
UniProt
B7NZS8
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Small ribosomal subunit protein eS10
Chain: L
Length: 149 amino acids
Theoretical weight: 17.16 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TPV3 (Residues: 1-149; Coverage: 90%)
Pfam: Plectin/S10 domain
InterPro:
Small ribosomal subunit protein eS10 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein eS10 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein eS10 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1TPV3  
114920406080100120140
 
50100150
UniProt
G1TPV3
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Small ribosomal subunit protein uS17
Chain: M
Length: 158 amino acids
Theoretical weight: 18.47 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TRM4 (Residues: 1-158; Coverage: 100%)
Gene name: RPS11
Pfam:
InterPro:
Small ribosomal subunit protein uS17 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein uS17 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein uS17 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1TRM4  
115820406080100120140
 
50100150
UniProt
G1TRM4
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Small ribosomal subunit protein eS12
Chain: N
Length: 132 amino acids
Theoretical weight: 14.54 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SFR8 (Residues: 1-132; Coverage: 100%)
Gene name: RPS12
Pfam: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
InterPro:
Small ribosomal subunit protein eS12 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein eS12 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein eS12 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1SFR8  
1132102030405060708090100110120130
 
50100
UniProt
G1SFR8
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Small ribosomal subunit protein uS15
Chain: O
Length: 151 amino acids
Theoretical weight: 17.26 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SP51 (Residues: 1-151; Coverage: 100%)
Gene name: RPS13
Pfam:
InterPro:
Small ribosomal subunit protein uS15 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein uS15 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein uS15 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1SP51  
115120406080100120140
 
50100150
UniProt
G1SP51
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Small ribosomal subunit protein uS11
Chain: P
Length: 168 amino acids
Theoretical weight: 18.13 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1T1F0 (Residues: 1-151; Coverage: 100%)
Gene name: RPS14
Pfam: Ribosomal protein S11
InterPro:
Small ribosomal subunit protein uS11 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein uS11 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein uS11 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1T1F0  
116820406080100120140160
 
50100150
UniProt
G1T1F0
Chains
Domains
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Small ribosomal subunit protein uS19
Chain: Q
Length: 145 amino acids
Theoretical weight: 17.05 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1U0Q2 (Residues: 1-145; Coverage: 100%)
Gene name: RPS15
Pfam: Ribosomal protein S19
InterPro:
Small ribosomal subunit protein uS19 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein uS19 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein uS19 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1U0Q2  
114520406080100120140
 
50100
UniProt
G1U0Q2
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Small ribosomal subunit protein uS9
Chain: R
Length: 172 amino acids
Theoretical weight: 19.21 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SGX4 (Residues: 1-146; Coverage: 100%)
Gene name: RPS16
Pfam: Ribosomal protein S9/S16
InterPro:
Small ribosomal subunit protein uS9 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein uS9 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein uS9 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1SGX4  
117220406080100120140160
 
50100150
UniProt
G1SGX4
Chains
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Small ribosomal subunit protein eS17
Chain: S
Length: 135 amino acids
Theoretical weight: 15.55 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TU13 (Residues: 1-135; Coverage: 100%)
Gene name: RPS17
Pfam: Ribosomal S17
InterPro:
Small ribosomal subunit protein eS17 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein eS17 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein eS17 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1TU13  
1135102030405060708090100110120130
 
50100
UniProt
G1TU13
Chains
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Small ribosomal subunit protein uS13
Chain: T
Length: 152 amino acids
Theoretical weight: 17.76 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TPG3 (Residues: 1-152; Coverage: 100%)
Gene name: RPS18
Pfam: Ribosomal protein S13/S18
InterPro:
Small ribosomal subunit protein uS13 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein uS13 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein uS13 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1TPG3  
115220406080100120140
 
50100150
UniProt
G1TPG3
Chains
Domains
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Small ribosomal subunit protein eS19
Chain: U
Length: 145 amino acids
Theoretical weight: 16.24 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TN62 (Residues: 1-145; Coverage: 100%)
Gene name: RPS19
Pfam: Ribosomal protein S19e
InterPro:
Small ribosomal subunit protein eS19 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein eS19 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein eS19 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1TN62  
114520406080100120140
 
50100
UniProt
G1TN62
Chains
Domains
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Small ribosomal subunit protein uS10
Chain: V
Length: 119 amino acids
Theoretical weight: 13.4 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SIZ2 (Residues: 1-119; Coverage: 100%)
Gene name: RPS20
Pfam: Ribosomal protein S10p/S20e
InterPro:
Small ribosomal subunit protein uS10 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein uS10 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein uS10 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1SIZ2  
1119102030405060708090100110
 
50100
UniProt
G1SIZ2
Chains
Domains
Secondary structure
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Small ribosomal subunit protein eS21
Chain: W
Length: 83 amino acids
Theoretical weight: 9.12 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TM82 (Residues: 1-83; Coverage: 100%)
Gene name: RPS21
Pfam: Ribosomal protein S21e
InterPro:
Small ribosomal subunit protein eS21 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein eS21 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein eS21 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1TM82  
1831020304050607080
 
20406080MQNDAGEFVDLYVPRKCSASNRIIGAKDHASIQMNVAEVDKVTGRFNGQFKTYAICGAIRRMGESDDSILRLAKADGIVSKNF
UniProt
G1TM82
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Small ribosomal subunit protein uS8
Chain: X
Length: 130 amino acids
Theoretical weight: 14.87 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TG89 (Residues: 1-130; Coverage: 100%)
Gene name: RPS15A
Pfam: Ribosomal protein S8
InterPro:
Small ribosomal subunit protein uS8 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein uS8 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein uS8 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1TG89  
1130102030405060708090100110120130
 
50100
UniProt
G1TG89
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Small ribosomal subunit protein uS12
Chain: Y
Length: 143 amino acids
Theoretical weight: 15.84 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SZ47 (Residues: 1-143; Coverage: 100%)
Gene name: RPS23
Pfam: Ribosomal protein S12/S23
InterPro:
Small ribosomal subunit protein uS12 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein uS12 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein uS12 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1SZ47  
114320406080100120140
 
50100
UniProt
G1SZ47
Chains
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40S ribosomal protein S24
Chain: Z
Length: 131 amino acids
Theoretical weight: 15.24 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1T3D8 (Residues: 1-131; Coverage: 100%)
Gene name: RPS24
Pfam: Ribosomal protein S24e
InterPro:
40S ribosomal protein S24 in PDB entry 7syk, assembly 1, front view.
40S ribosomal protein S24 in PDB entry 7syk, assembly 1, side view.
40S ribosomal protein S24 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1T3D8  
1131102030405060708090100110120130
 
50100
UniProt
G1T3D8
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Small ribosomal subunit protein eS25
Chain: a
Length: 124 amino acids
Theoretical weight: 13.65 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TDB3 (Residues: 1-124; Coverage: 100%)
Gene name: RPS25
Pfam: S25 ribosomal protein
InterPro:
Small ribosomal subunit protein eS25 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein eS25 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein eS25 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1TDB3  
1124102030405060708090100110120
 
50100
UniProt
G1TDB3
Chains
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Small ribosomal subunit protein eS26
Chain: b
Length: 101 amino acids
Theoretical weight: 11.65 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TFE8 (Residues: 2-102; Coverage: 88%)
Gene name: RPS26
Pfam: Ribosomal protein S26e
InterPro:
Small ribosomal subunit protein eS26 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein eS26 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein eS26 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1TFE8  
1101102030405060708090100
 
50100TKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPPPRFR
UniProt
G1TFE8
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Small ribosomal subunit protein eS27
Chain: c
Length: 84 amino acids
Theoretical weight: 9.48 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TZ76 (Residues: 1-84; Coverage: 100%)
Gene name: RPS27
Pfam: Ribosomal protein S27
InterPro:
Small ribosomal subunit protein eS27 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein eS27 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein eS27 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1TZ76  
1841020304050607080
 
20406080MPLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH
UniProt
G1TZ76
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Small ribosomal subunit protein eS28
Chain: d
Length: 69 amino acids
Theoretical weight: 7.86 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TIB4 (Residues: 1-69; Coverage: 100%)
Gene name: RPS28
Pfam: Ribosomal protein S28e
InterPro:
Small ribosomal subunit protein eS28 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein eS28 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein eS28 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1TIB4  
1695101520253035404550556065
 
204060MDTSRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLTLLESEREARRLR
UniProt
G1TIB4
Chains
Domains
Secondary structure
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Small ribosomal subunit protein uS14
Chain: e
Length: 56 amino acids
Theoretical weight: 6.69 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1U7M4 (Residues: 1-56; Coverage: 100%)
Gene name: RPS29
Pfam: Ribosomal protein S14p/S29e
InterPro:
Small ribosomal subunit protein uS14 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein uS14 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein uS14 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1U7M4  
156510152025303540455055
 
2040MGHQQLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFIKLD
UniProt
G1U7M4
Chains
Domains
Secondary structure
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Sequence conservation
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Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein
Chain: f
Length: 133 amino acids
Theoretical weight: 14.5 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1T8A2 (Residues: 1-133; Coverage: 100%)
Gene name: FAU
Pfam:
InterPro:
Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein in PDB entry 7syk, assembly 1, front view.
Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein in PDB entry 7syk, assembly 1, side view.
Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1T8A2  
1133102030405060708090100110120130
 
50100
UniProt
G1T8A2
PRO_0000460083
PRO_0000460084
Chains
Domains
Secondary structure
Interaction interfaces
Sequence conservation
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Ubiquitin-ribosomal protein eS31 fusion protein
Chain: g
Length: 188 amino acids
Theoretical weight: 21.43 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SK22 (Residues: 18-156; Coverage: 89%)
Gene name: RPS27A
Pfam:
InterPro:
Ubiquitin-ribosomal protein eS31 fusion protein in PDB entry 7syk, assembly 1, front view.
Ubiquitin-ribosomal protein eS31 fusion protein in PDB entry 7syk, assembly 1, side view.
Ubiquitin-ribosomal protein eS31 fusion protein in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1SK22  
118820406080100120140160180
 
50100150
UniProt
G1SK22
PRO_0000460079
PRO_0000460080
Chains
Domains
Secondary structure
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Ligand binding sites
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Small ribosomal subunit protein RACK1
Chain: h
Length: 317 amino acids
Theoretical weight: 35.12 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SJB4 (Residues: 1-317; Coverage: 100%)
Gene name: RACK1
Pfam: WD domain, G-beta repeat
InterPro:
Small ribosomal subunit protein RACK1 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein RACK1 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein RACK1 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: G1SJB4  
131720406080100120140160180200220240260280300
 
100200300
UniProt
G1SJB4
Chains
Domains
Secondary structure
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Small ribosomal subunit protein eS32
Chain: n
Length: 25 amino acids
Theoretical weight: 3.47 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A087WNH4 (Residues: 1-25; Coverage: 100%)
Gene name: RPL41
Pfam: Ribosomal protein L41
InterPro: Large ribosomal subunit protein eS32
Small ribosomal subunit protein eS32 in PDB entry 7syk, assembly 1, front view.
Small ribosomal subunit protein eS32 in PDB entry 7syk, assembly 1, side view.
Small ribosomal subunit protein eS32 in PDB entry 7syk, assembly 1, top view.
PDBe-KB: UniProt Coverage View: A0A087WNH4  
12524681012141618202224
 
1020MRAKWRKKRMRRLKRKRRKMRQRSK
UniProt
A0A087WNH4
Chains
Domains
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RNA chain 2
Name: 18S Ribosomal RNA
Representative chains: 2
Length: 1870 nucleotides
Theoretical weight: 603.1 KDa
Rfam: Eukaryotic small subunit ribosomal RNA
18S Ribosomal RNA in PDB entry 7syk, assembly 1, front view.
18S Ribosomal RNA in PDB entry 7syk, assembly 1, side view.
18S Ribosomal RNA in PDB entry 7syk, assembly 1, top view.
118702004006008001,0001,2001,4001,6001,800
 
50010001500
Chains
Chain A (auth 2)
Rfam
Interaction interfaces
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RNA chain z
Name: HCV IRES
Representative chains: z
Length: 400 nucleotides
Theoretical weight: 128.75 KDa
Rfam: Hepatitis C virus internal ribosome entry site
HCV IRES in PDB entry 7syk, assembly 1, front view.
HCV IRES in PDB entry 7syk, assembly 1, side view.
HCV IRES in PDB entry 7syk, assembly 1, top view.
140050100150200250300350400
 
100200300400
Chains
Chain JA (auth z)
Rfam
Interaction interfaces
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