Function and Biology Details
Reactions catalysed:
Farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate
Geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125435 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
Molecule details ›
Chain: A
Length: 349 amino acids
Theoretical weight: 40.91 KDa
Source organism: Cryptococcus neoformans var. grubii H99
Expression system: Escherichia coli
UniProt:
Sequence domains: Protein prenyltransferase alpha subunit repeat
Length: 349 amino acids
Theoretical weight: 40.91 KDa
Source organism: Cryptococcus neoformans var. grubii H99
Expression system: Escherichia coli
UniProt:
- Canonical:
J9VSJ6 (Residues: 1-335; Coverage: 100%)
Sequence domains: Protein prenyltransferase alpha subunit repeat
Protein farnesyltransferase subunit beta
Molecule details ›
Chain: B
Length: 520 amino acids
Theoretical weight: 56.81 KDa
Source organism: Cryptococcus neoformans var. grubii H99
Expression system: Escherichia coli
UniProt:
Sequence domains: Prenyltransferase and squalene oxidase repeat
Length: 520 amino acids
Theoretical weight: 56.81 KDa
Source organism: Cryptococcus neoformans var. grubii H99
Expression system: Escherichia coli
UniProt:
- Canonical: T2BPA1 (Residues: 1-520; Coverage: 100%)
Sequence domains: Prenyltransferase and squalene oxidase repeat
