› 7t15

X-ray diffraction
2.05Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172766 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gag protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 231 amino acids
Theoretical weight: 25.32 KDa
Source organism: Simian immunodeficiency virus - cpz
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q1A241 (Residues: 123-353; Coverage: 47%)
Gene name: gag
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P63
Unit cell:
a: 90.669Å b: 90.669Å c: 116.785Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.203 0.202 0.231
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Function and regulation of cGAS-STING signaling in infectious diseases.
Du et al. (2023)
1 more

1 mention without citation

Evasion of cGAS and TRIM5 defines pandemic HIV.
Zuliani-Alvarez et al. (2022)