7t9b

Electron Microscopy
3.72Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetradecamer (preferred)
PDBe Complex ID:
PDB-CPX-225832 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (12 distinct):
HIV-1 Envelope ApexGT5 gp120 Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 473 amino acids
Theoretical weight: 53.2 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
Transmembrane protein gp41 Chains: B, D, F
Molecule details ›
Chains: B, D, F
Length: 153 amino acids
Theoretical weight: 17.13 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2N0S6 (Residues: 509-661; Coverage: 18%)
Gene name: env
Sequence domains: Retroviral envelope protein
RM20A3 Fab Heavy Chain Chains: J, M, O
Molecule details ›
Chains: J, M, O
Length: 125 amino acids
Theoretical weight: 13.51 KDa
Source organism: Macaca mulatta
Expression system: Homo sapiens
RM20A3 Fab Light Chain Chains: K, N, P
Molecule details ›
Chains: K, N, P
Length: 128 amino acids
Theoretical weight: 13.51 KDa
Source organism: Macaca mulatta
Expression system: Homo sapiens
GT5-d42.16 Fab Heavy Chain Chain: H
Molecule details ›
Chain: H
Length: 134 amino acids
Theoretical weight: 15.13 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
GT5-d42.16 Fab Light Chain Chain: L
Molecule details ›
Chain: L
Length: 107 amino acids
Theoretical weight: 11.61 KDa
Source organism: Mus musculus
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer : NEW Components: NAG, FUC
1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
Resolution: 3.72Å
Relevant EMDB volumes: EMD-25755
Expression system: Homo sapiens