› 7t9x

X-ray diffraction
1.52Å resolution

Saccharomyces cerevisiae Pex12 RING domain

Released:
DOI: 10.2210/pdb7t9x/pdb
PDB entry 7t9x coloured by chain, front view.
PDB entry 7t9x coloured by chain, side view.
PDB entry 7t9x coloured by chain, top view.
Source organism: Bacteria
Primary publication:
A peroxisomal ubiquitin ligase complex forms a retrotranslocation channel.
Feng P, Wu X, Erramilli SK, Paulo JA, Knejski P, Gygi SP, Kossiakoff AA, Rapoport TA
Nature (2022)
PMID: 35768507

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170020 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peroxisome assembly protein 12 Chains: A, B
Molecule details ›
Chains: A, B
Length: 73 amino acids
Theoretical weight: 8.01 KDa
Source organism: Bacteria
Expression system: Bacteria
UniProt:
  • Canonical: Q04370 (Residues: 330-397; Coverage: 17%)
Gene names: PEX12, YM9711.16C, YMR026C

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P21
Unit cell:
a: 27.578Å b: 32.922Å c: 72.488Å
α: 90° β: 100.715° γ: 90°
R-values:
R R work R free
0.187 0.186 0.197
Expression system: Bacteria

Quick links

Citations

2 review citations

Non-lysine ubiquitylation: Doing things differently.
Kelsall IR. (2022)
1 more