7te9

Electron Microscopy
3.92Å resolution

Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 class1

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
PDBe Complex ID:
PDB-CPX-211105 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Glutamate receptor ionotropic, NMDA 1 Chains: A, C
Molecule details ›
Chains: A, C
Length: 862 amino acids
Theoretical weight: 96.94 KDa
Source organism: Rattus norvegicus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P35439 (Residues: 1-190, 191-838; Coverage: 89%)
Gene names: Grin1, Nmdar1
Sequence domains:
Glutamate receptor ionotropic, NMDA 2B Chains: B, D
Molecule details ›
Chains: B, D
Length: 822 amino acids
Theoretical weight: 92.32 KDa
Source organism: Rattus norvegicus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q00960 (Residues: 31-852; Coverage: 57%)
Gene name: Grin2b
Sequence domains:
Fab2 heavy chain Chains: H, M
Molecule details ›
Chains: H, M
Length: 223 amino acids
Theoretical weight: 23.91 KDa
Source organism: Mus musculus
Fab2 light chain Chains: L, N
Molecule details ›
Chains: L, N
Length: 213 amino acids
Theoretical weight: 23.57 KDa
Source organism: Mus musculus

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.92Å
Relevant EMDB volumes: EMD-25843
Expression system: Spodoptera frugiperda