› 7tou

Electron Microscopy
3.24Å resolution

Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 3-RBD-down conformation; consensus state D1

Released:
DOI: 10.2210/pdb7tou/pdb
PDB entry 7tou coloured by chain, front view.
PDB entry 7tou coloured by chain, side view.
PDB entry 7tou coloured by chain, top view.
Source organism: Severe acute respiratory syndrome coronavirus 2
Primary publication:
Structural diversity of the SARS-CoV-2 Omicron spike.
Gobeil SM, Henderson R, Stalls V, Janowska K, Huang X, May A, Speakman M, Beaudoin E, Manne K, Li D, Parks R, Barr M, Deyton M, Martin M, Mansouri K, Edwards RJ, Eaton A, Montefiori DC, Sempowski GD, Saunders KO, Wiehe K, Williams W, Korber B, Haynes BF, Acharya P
Mol Cell 82 2050-2068.e6 (2022)
PMID: 35447081
Related structures: EMD-26038

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-144650 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1286 amino acids
Theoretical weight: 142.24 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-1208; Coverage: 95%)
Gene names: 2, S
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Ligand NAG 28 x NAG
1 bound ligand:
Ligand NAG 33 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.24Å
Relevant EMDB volumes: EMD-26038
Expression system: Homo sapiens

Quick links

Citations

10 review citations

PDBx/mmCIF Ecosystem: Foundational Semantic Tools for Structural Biology.
Westbrook et al. (2022)
9 more

4 mentions without citation

Evolution of the SARS-CoV-2 Omicron spike.
Parsons et al. (2023)
3 more