Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
NTP + H(2)O = NDP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetradecamer (preferred)
PDBe Complex ID:
PDB-CPX-222275 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (6 distinct):
VP1
Molecule details ›
Chains: a, e, i
Length: 298 amino acids
Theoretical weight: 33.23 KDa
Source organism: Coxsackievirus A21
UniProt:
Length: 298 amino acids
Theoretical weight: 33.23 KDa
Source organism: Coxsackievirus A21
UniProt:
- Canonical:
Q7T7N6 (Residues: 582-879; Coverage: 14%)
Capsid protein VP2
Molecule details ›
Chains: b, f, j
Length: 272 amino acids
Theoretical weight: 29.92 KDa
Source organism: Coxsackievirus A21
UniProt:
Length: 272 amino acids
Theoretical weight: 29.92 KDa
Source organism: Coxsackievirus A21
UniProt:
- Canonical: P22055 (Residues: 70-341; Coverage: 12%)
Capsid protein VP3
Molecule details ›
Chains: c, g, k
Length: 240 amino acids
Theoretical weight: 26.6 KDa
Source organism: Coxsackievirus A21
UniProt:
Length: 240 amino acids
Theoretical weight: 26.6 KDa
Source organism: Coxsackievirus A21
UniProt:
- Canonical: P22055 (Residues: 342-581; Coverage: 11%)
Capsid protein VP4
Molecule details ›
Chains: d, h, l
Length: 69 amino acids
Theoretical weight: 7.44 KDa
Source organism: Coxsackievirus A21
UniProt:
Length: 69 amino acids
Theoretical weight: 7.44 KDa
Source organism: Coxsackievirus A21
UniProt:
- Canonical: P22055 (Residues: 1-69; Coverage: 3%)
