7tua

X-ray diffraction
1.35Å resolution

Human Synaptotagmin-1 C2B Y312F without Ca2+

Released:
Source organism: Homo sapiens
Entry authors: Dominguez MJ, Karmakar S, Fuson KL, Sutton RB

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149302 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Synaptotagmin-1 Chain: A
Molecule details ›
Chain: A
Length: 157 amino acids
Theoretical weight: 17.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P21579 (Residues: 272-422; Coverage: 36%)
Gene names: SVP65, SYT, SYT1
Sequence domains: C2 domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P3221
Unit cell:
a: 54.44Å b: 54.44Å c: 104.07Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.179 0.178 0.199
Expression system: Escherichia coli BL21(DE3)