› 7twd

X-ray diffraction
2.11Å resolution

Structure of AAGAB C-terminal dimerization domain

Released:
DOI: 10.2210/pdb7twd/pdb
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PDB entry 7twd coloured by chain, front view.
PDB entry 7twd coloured by chain, side view.
PDB entry 7twd coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Oligomer-to-monomer transition underlies the chaperone function of AAGAB in AP1/AP2 assembly.
Tian Y, Datta I, Yang R, Wan C, Wang B, Crisman L, He H, Brautigam CA, Li S, Shen J, Yin Q
OpenAccess logo Proc Natl Acad Sci U S A 120 e2205199120 (2023)
PMID: 36598941

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180143 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha- and gamma-adaptin-binding protein p34 Chains: A, B
Molecule details ›
Chains: A, B
Length: 45 amino acids
Theoretical weight: 5.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6PD74 (Residues: 258-301; Coverage: 14%)
Gene name: AAGAB

Ligands and Environments

1 bound ligand:
Ligand PO4 2 x PO4
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P6122
Unit cell:
a: 47.539Å b: 47.539Å c: 191.394Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.217 0.212 0.26
Expression system: Escherichia coli

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