PDB 7txd structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Biochemical function:

structural molecule activity

Biological process:

cell adhesion

Cellular component:

membrane

Sequence domains:

5 more domains

Structure analysis Details

Assembly composition:

hetero dodecamer (preferred)

PDBe Complex ID:

PDB-CPX-199818 (preferred)

Entry contents:

4 distinct polypeptide molecules

Macromolecules (8 distinct):

Envelope glycoprotein gp160 Chains: A, C, E

Molecule details ›

Chains: A, C, E
Length: 481 amino acids
Theoretical weight: 54.06 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:

Canonical: Q2N0S6 (Residues: 30-505; Coverage: 55%)

Gene name: env
Sequence domains: Envelope glycoprotein GP120

Transmembrane protein gp41 Chains: B, D, F

Molecule details ›

Chains: B, D, F
Length: 153 amino acids
Theoretical weight: 17.15 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:

Canonical: Q2N0S6 (Residues: 509-661; Coverage: 18%)

Gene name: env
Sequence domains: Retroviral envelope protein

T-cell surface glycoprotein CD4 Chains: G, H, I

Molecule details ›

Chains: G, H, I
Length: 185 amino acids
Theoretical weight: 20.5 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:

Canonical: P01730 (Residues: 26-208; Coverage: 42%)

Gene name: CD4
Sequence domains:

Broadly neutralizing darpin bnd.9 Chains: J, K, L

Molecule details ›

Chains: J, K, L
Length: 196 amino acids
Theoretical weight: 21.21 KDa
Source organism: synthetic construct
Expression system: Homo sapiens