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A novel compound mimics the structural and functional effects of the full agonist glycine on glycine channels-desenstized state

Source organism: Danio rerio
Biochemical function: transmitter-gated monoatomic ion channel activity
Biological process: monoatomic ion transmembrane transport
Cellular component: postsynaptic membrane

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF02932
Domain description: Neurotransmitter-gated ion-channel transmembrane region
Occurring in:
  1. Glycine receptor subunit alphaZ1
The deposited structure of PDB entry 7u2m contains 5 copies of Pfam domain PF02932 (Neurotransmitter-gated ion-channel transmembrane region) in Glycine receptor subunit alphaZ1. Showing 1 copy in chain A.

PF02931
Domain description: Neurotransmitter-gated ion-channel ligand binding domain
Occurring in:
  1. Glycine receptor subunit alphaZ1
The deposited structure of PDB entry 7u2m contains 5 copies of Pfam domain PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) in Glycine receptor subunit alphaZ1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR006201
Domain description: Neurotransmitter-gated ion-channel
Occurring in:
  1. Glycine receptor subunit alphaZ1
IPR006028
Domain description: Gamma-aminobutyric acid A receptor/Glycine receptor alpha
Occurring in:
  1. Glycine receptor subunit alphaZ1
IPR008127
Domain description: Glycine receptor alpha
Occurring in:
  1. Glycine receptor subunit alphaZ1
IPR008128
Domain description: Glycine receptor alpha1
Occurring in:
  1. Glycine receptor subunit alphaZ1
IPR036734
Domain description: Neurotransmitter-gated ion-channel ligand-binding domain superfamily
Occurring in:
  1. Glycine receptor subunit alphaZ1
IPR006029
Domain description: Neurotransmitter-gated ion-channel transmembrane domain
Occurring in:
  1. Glycine receptor subunit alphaZ1
IPR036719
Domain description: Neurotransmitter-gated ion-channel transmembrane domain superfamily
Occurring in:
  1. Glycine receptor subunit alphaZ1
IPR038050
Domain description: Neuronal acetylcholine receptor
Occurring in:
  1. Glycine receptor subunit alphaZ1
IPR018000
Domain description: Neurotransmitter-gated ion-channel, conserved site
Occurring in:
  1. Glycine receptor subunit alphaZ1
IPR006202
Domain description: Neurotransmitter-gated ion-channel ligand-binding domain
Occurring in:
  1. Glycine receptor subunit alphaZ1

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